Rapid typing of the codon 129 polymorphism of the human prion protein gene by combined real-time PCR and melting curve analysis

Clinical Laboratory

Volumn 48, Issue 1-2, 2002, Pages 25-30

  Schalasta, Gunnar ^a   Roth, Bernhard ^a   Enders, Gisela ^a  

^a Medical Diagnostic Laboratory   (Germany)

Author keywords

Codon 129; Genotyping; LightCycler; New variant Creutzfeldt Jakob disease (vCJD); Prion protein (PrP)

Indexed keywords

METHIONINE; OLIGONUCLEOTIDE; PRION PROTEIN; VALINE;

ALLELE; AMINO ACID SEQUENCE; ARTICLE; AUTOMATION; BOVINE SPONGIFORM ENCEPHALOPATHY; CAUCASIAN; CODON; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; DIAGNOSTIC ACCURACY; GENE AMPLIFICATION; GENE SEQUENCE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETIC VARIABILITY; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; MELTING POINT; POLYMERASE CHAIN REACTION; RESTRICTION MAPPING; SEQUENCE ANALYSIS; COMPARATIVE STUDY; DNA DENATURATION; GENETIC SCREENING; GENETICS; GENOTYPE; METHODOLOGY; PRION; REPRODUCIBILITY; SINGLE NUCLEOTIDE POLYMORPHISM; STANDARD; TEMPERATURE; TIME; VALIDATION STUDY;

CODON; GENETIC SCREENING; GENOTYPE; HUMANS; NUCLEIC ACID DENATURATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PRIONS; REPRODUCIBILITY OF RESULTS; TEMPERATURE; TIME FACTORS;

EID: 0036151163     PISSN: 14336510     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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