Altered electromechanical coupling in the renal microvasculature during the early stage of diabetes mellitus

Clinical and Experimental Pharmacology and Physiology

Volumn 29, Issue 1-2, 2002, Pages 143-148

  Carmines, Pamela K ^a   Fujiwara, Keiji ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Afferent arteriole; ATP sensitive potassium channels; Diabetes mellitus; Efferent arteriole; Rat; Renal circulation; Voltage gated calcium channels

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; ADENOSINE TRIPHOSPHATE; CALCIUM CHANNEL; CALCIUM ION; GLUCOSE; POTASSIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; BLOOD VESSEL DIAMETER; BLOOD VESSEL TONE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; DIABETIC NEPHROPATHY; EXCITATION CONTRACTION COUPLING; EXTRACELLULAR SPACE; GLOMERULUS; GLOMERULUS FILTRATION; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY BLOOD VESSEL; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MICROVASCULATURE; NONHUMAN; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; VASODILATATION;

ANIMALS; DIABETES MELLITUS, TYPE 1; DIABETIC NEPHROPATHIES; HUMANS; KIDNEY; MICROCIRCULATION;

EID: 0036150980     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2002.03616.x     Document Type: Article

References (49)

1. Mechanisms of diabetic hyperfiltration
2. Pathogenesis of diabetic glomerulopathy: Hemodynamic considerations
3. Paracrine regulation of the renal microcirculation
4. Effects of calcium channel blockade on renal vascular resistance responses to changes in perfusion pressure and angiotensin-converting enzyme inhibition in dogs
5. Angiotensin II-induced changes in smooth muscle calcium in rat renal arterioles
6. 2+ from intracellular stores
7. Cellular mechanisms mediating rat renal microvascular constriction by angiotensin II
8. Ionic currents and endo-thelin signaling in smooth muscle cells from rat renal resistance arteries
9. 2+ channel, and it is functionally important in renal afferent arterioles
10. + channels in the rabbit
11. + channels
12. + channels in rat renal arterioles
13. +-channel activity
14. + channel in renal arterioles
15. + channels on rat renal arteriolar responses to depolarizing agonists
16. Differential regulation of cytosolic calcium between afferent arteriolar smooth muscle cells from mouse kidney
17. Segment-specific effect of chloride channel blockade on rat renal arteriolar contractile responses to angiotensin II
18. Attenuation of endothelin effects by a chloride channel inhibitor, indanyloxyacetic acid
19. Blockade of chloride channels by DIDS stimulates renin release and inhibits contraction of afferent arterioles
20. Role of chloride channels in afferent arteriolar constriction
21. Chloride is essential for contraction of afferent arterioles after agonists and potassium
22. 2+] in renal arterioles
23. KCl and angiotensin responses in isolated rat renal arterioles: Effects of diltiazem and low-calcium medium
24. i responses to ANG II
25. Disparate effects of Ca channel blockade on afferent and efferent arteriolar responses to ANG II
26. Renal microvascular effects of endothelin
27. Membrane potential measurements in renal afferent and efferent arterioles: Actions of angiotensin II
28. 2+ entry
29. Juxtamedullary microvascular dysfunction during the hyperfiltration stage of diabetes mellitus
30. Impaired myogenic responsiveness of the afferent arteriole in streptozotocin-induced diabetic rats: Role of eicosanoid derangements
31. Homeostatic efficiency of tubulo-glomerular feedback is reduced in established diabetes mellitus in rats
32. Imparied autoregulation of glomerular filtration rate and renal plasma flow in short-term insulin-dependent diabetics
33. Calcium and potassium currents in ventricular myocytes isolated from diabetic rats
34. 2+ currents in ventricular myocytes from rats with chronic diabetes
35. Expression of calcium channel mRNAs in rat pancreatic islets and downregulation after glucose infusion
36. 2+-channels during the development of diabetic cardiomyopathy
37. Increase of voltage-sensitive calcium channels and calcium accumulation in skeletal muscles of streptozocin-induced diabetic rats
38. 3H]PN200-100 binding to cardiac muscle membrane in streptozotocin-induced diabetic rats
39. Acute effect of calcium and insulin on hyperfiltration of early diabetes
40. Effect of elevated extracellular glucose concentrations on transmembrane calcium ion fluxes in cultured rat VSMC
41. Functional impairment of renal afferent arteriolar voltage-gated calcium channels in rats with diabetes mellitus
42. 2+ influx response to depolarization of isolated preglomerular microvascular smooth muscle cells
43. Advanced glycosylation endproducts. Role in diabetic and non-diabetic vascular disease
44. Glucose-induced vascular smooth muscle dysfunction. The role of protein kinase C
45. Hyperglycemic pseudo-hypoxia and diabetic complications
46. + channels
47. + channels on afferent arteriolar diameter in diabetes mellitus
48. Altered renal expression of the insulin-responsive glucose transporter GLUT4 in experimental diabetes mellitus
49. Potassium channel function in vascular disease