Intramacrophage passage of Mycobacterium tuberculosis and M. avium complex alters the drug susceptibilities of the organisms as determined by intracellular susceptibility testing using macrophages and type II alveolar epithelial cells

Antimicrobial Agents and Chemotherapy

Volumn 46, Issue 2, 2002, Pages 519-521

  Tomioka, Haruaki ^a   Sato, Katsumasa ^a   Sano, Chiaki ^a   Sano, Keisuke ^a   Shimizu, Toshiaki ^a  

^a SHIMANE UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CLARITHROMYCIN; LEVOFLOXACIN; RIFALAZIL;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM CULTURE; GROWTH INHIBITION; HUMAN; HUMAN CELL; MACROPHAGE; MYCOBACTERIUM AVIUM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL;

ANTI-BACTERIAL AGENTS; ANTIBIOTICS, ANTITUBERCULAR; CELLS, CULTURED; CLARITHROMYCIN; EPITHELIAL CELLS; HUMANS; MACROPHAGES; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM AVIUM COMPLEX; MYCOBACTERIUM TUBERCULOSIS; OFLOXACIN; RIFAMYCINS;

EID: 0036150257     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.46.2.519-521.2002     Document Type: Article

References (12)

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7. Comparison of in vitro models for the study of Mycobacterium tuberculosis invasion and intracellular replication
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10. Antimicrobial activities of levofloxacin, clarithromycin, and KRM-1648 against Mycobacterium tuberculosis and Mycobacterium avium complex replicating within Mono Mac 6 human macrophage and A-549 type II alveolar cell lines
11. Prospects for development of new antimicrobial drugs, with special reference to a new benzoxazinorifamycin, KRM-1648
12. Establishment of a human cell line (Mono Mac 6) with characteristics of mature monocytes