Physicochemical characterization and solubility analysis of thalidomide and its N-alkyl analogs

Pharmaceutical Research

Volumn 19, Issue 1, 2002, Pages 13-19

  Goosen, C ^a,b   Laing, T J ^b   Plessis, J D ^a   Goosen, T C ^a,c   Flynn, G L ^b  

^a NORTH WEST UNIVERSITY   (South Africa)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Lipophilicity; N alkyl analogs; Solubility; Solubility parameter; Thalidomide

Indexed keywords

N METHYL THALIDOMIDE; N PENTYL THALIDOMIDE; N PROPYL THALIDOMIDE; OCTANOL; THALIDOMIDE; THALIDOMIDE DERIVATIVE; UNCLASSIFIED DRUG; WATER;

ARTICLE; CRYSTAL STRUCTURE; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; DRUG SYNTHESIS; FAST ATOM BOMBARDMENT MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHOBICITY; METHYLATION; PH; PRIORITY JOURNAL;

ALKYLATION; CALORIMETRY, DIFFERENTIAL SCANNING; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; SOLUBILITY; THALIDOMIDE;

EID: 0036149192     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1013643013244     Document Type: Article

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