Modeling the pharmacokinetics and pharmacodynamics of a unique oral hypoglycemic agent using neural networks

Pharmaceutical Research

Volumn 19, Issue 1, 2002, Pages 87-91

  Haidar, S H ^a   Johnson, S B ^a   Fossler, M J ^b   Hussain, A S ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b DUPONT COMPANY   (United States)

Author keywords

Models; Neural networks; Pharmacokinetics pharmacodynamics; Repaglinide; Type 2 diabetes

Indexed keywords

GLUCOSE; REPAGLINIDE;

AREA UNDER THE CURVE; ARTICLE; ARTIFICIAL NEURAL NETWORK; BODY WEIGHT; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG METABOLISM; DRUG STRUCTURE; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MALE; MODEL; NON INSULIN DEPENDENT DIABETES MELLITUS; PHARMACODYNAMICS; PHARMACOKINETICS; PRIORITY JOURNAL; SEX DIFFERENCE;

BLOOD GLUCOSE; CARBAMATES; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; HYPOGLYCEMIC AGENTS; MALE; NEURAL NETWORKS (COMPUTER); PIPERIDINES; PREDICTIVE VALUE OF TESTS;

EID: 0036149005     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1013611617787     Document Type: Article

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