Quantification of lipopolysaccharides in outer membrane vesicle vaccines against meningococcal disease. High-performance liquid chromatographic determination of the constituent 3-hydroxy-lauric acid

Biologicals

Volumn 30, Issue 1, 2002, Pages 7-13

  Lyngby, Janne ^a   Olsen, Linda H ^a   Eidem, Tove ^a   Lundanes, Elsa ^b   Jantzen, Erik ^a  

^a NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Endotoxin; Fatty acid marker; HPLC UV; Lipopolysaccharide; Vaccine quality control

Indexed keywords

3 HYDROXYDODECANOIC ACID; ACETONITRILE; ESTER; LAURIC ACID DERIVATIVE; LIPOPOLYSACCHARIDE; MENINGOCOCCUS VACCINE; OUTER MEMBRANE VESICLE VACCINE; UNCLASSIFIED DRUG; WATER;

ARTICLE; DRUG HYDROLYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID ANALYSIS; MEMBRANE VESICLE; NEISSERIA MENINGITIDIS; PRIORITY JOURNAL; QUALITY CONTROL; REVERSED PHASE LIQUID CHROMATOGRAPHY; SOLID PHASE EXTRACTION;

EID: 0036148708     PISSN: 10451056     EISSN: None     Source Type: Journal    
DOI: 10.1006/biol.2001.0285     Document Type: Article

References (25)

1. Effect of outer membrane vesicle vaccine against group B meningococcal disease in Norway
2. Production, characterization and control of MenB-vaccine "Folkehelsa": An outer membrane vesicle vaccine against group B meningococcal disease
3. Safety and immunogenicity of a Neisseria meningitidis type 2 protein vaccine in animals and humans
4. Serotype determinant protein of Neisseria meningitidis. Large scale preparation by direct detergent treatment of the bacterial cells
5. Systemic meningococcal disease: Clinical pictures and pathophysiological background
6. The class 1 outer membrane protein of Neisseria meningitidis produced in Bacillus subtilis can give rise to protective immunity
7. Measurements of lipopolysaccharide (endotoxin) in meningococcal protein and polysaccharide preparations for vaccine usage
8. Immunogenicity of outer membrane proteins in a lipopolysaccharide-deficient mutant of Neisseria meningitidis: Influence of adjuvants on the immune respons
9. Immune response of infants and children to disseminated infections with Neisseria meningitidis
10. Bacterial antibody responses of juvenile rhesus monkeys immunized with group B Neisseria meningitidis capsular polysaccharide-protein conjugate vaccines
11. Lipopolysaccharide, lipid A, and liposomes containing lipid A as immunologic adjuvants
12. Effect of aluminium hydroxide and meningococcal serogroup C polysaccharide on the immunogenicity and reactogenicity of a group B Neisseria meningitidis outer membrane vesicle vaccine
13. Heterogenity of molecular size and antigenic expression within lipopolysaccharides of individual strains of Neisseria gonorrhoeae and Neisseria meningitidis
14. Structure of the sialylated L3 lipopolysaccharide of Neisseria meningitidis
15. Structural characterization of the lipid A component of patogenic Neisseria meningitidis
16. Analysis of cellular constituents from gram-negative bacteria
17. Outer membrane protein vesicle vaccines for meningococcal disease
18. Analysis of lipopolysaccharides by methanolysis, trifluoroacetylation, and gas chromatography on a fused-silica capillary column
19. Meningococcal endotoxin in lethal septic shock plasma studied by gas chromatography, mass spectrometry, ultracentrifugation, and electron microscopy
20. Studies on the gram-negative cell wall, I. Evidence for the role of 2-keto-3-deoxyoctonate in the lipopolysaccharide of Salmonella typhimurium
21. Measurements of lipopolysaccharide (endotoxin) in meningococcal protein and polysaccharide preparations for vaccine usage
22. Heterogeneity of lipopolysaccharides of Neisseria meningitidis revealed by thin-layer chromatography combined with monoclonal antibodies
23. 3-Hydroxymyristic acid as a measure of endotoxin in cotton lint and dust
24. Analysis of lipopolysaccharide (lipid A) fatty acids
25. Artifacts produced by acidic hydrolysis of lipids containing 3-hydroxyalkanoic acids