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Volumn 24, Issue 1, 2002, Pages 85-90

New antiepileptic drugs currently in clinical trials: Is there a strategy in their development?

Author keywords

New antiepileptic drugs; Pharmacodynamic based drug design; Pharmacokinetic based drug design; Second generation antiepileptic drugs

Indexed keywords

1 (4 CHLOROPHENYL) 4 MORPHOLINO 3 IMIDAZOLIN 2 ONE; 2 HYDROXYPROPYLVALPROMIDE; 2 ISOPROPYLVALERAMIDE; ABS 103; ANTICONVULSIVE AGENT; CONANTOKIN G; ETIRACETAM; FELBAMATE; FLUOROFELBAMATE; GABAPENTIN; HARKOSERIDE; ISOVALERAMIDE; LAMOTRIGINE; N METHYL 2,2,3,3 TETRAMETHYLCYCLOPROPANECARBOXAMIDE; NEW DRUG; OXCARBAZEPINE; PREGABALIN; RETIGABINE; RUFINAMIDE; SAFINAMIDE; SPD 421; TALAMPANEL; TIAGABINE; TOPIRAMATE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALNOCTAMIDE; VALPROIC ACID DERIVATIVE; VALROCEMIDE; VIGABATRIN; ZONISAMIDE;

EID: 0036146487     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-200202000-00015     Document Type: Conference Paper
Times cited : (22)

References (21)
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  • 9
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    • Valproic acid induced neural tube defects in mice and humans: Aspects of chirality, alternative drug development, pharmacokinetics, and possible mechanism
    • (1991) Pharmacol Toxicol , vol.69 , pp. 310-321
    • Nau, H.1    Hauck, E.S.2    Ehlers, K.3
  • 12
    • 0026749339 scopus 로고
    • Single-dose tolerance and pharmacokinetics of 2-n propyl-2(E)-pentanoate (Δ2(e)-valproate) in healthy male volunteers
    • (1992) Pharm Weekbl Sci , vol.14 , pp. 152-158
    • Dusing, R.H.1
  • 13
    • 0003164189 scopus 로고    scopus 로고
    • A new analogue of valproic acid with improved anticonvulsant properties and low teratogenic and neurotoxic potential in experimental animals
    • (1998) Epilepsia , vol.39 , pp. 42
    • Nau, H.1    Ellerbeck, U.2    Radatz, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.