Rapid intracellular degradation of a truncated mutant protein S (Q522X)

Thrombosis and Haemostasis

Volumn 87, Issue 1, 2002, Pages 171-172

  Yamazaki, Tomio ^a   Saito, Hidehiko ^a   Dahlbäck, Björn ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; PROTEIN S;

ANIMAL CELL; CELL STRAIN COS1; GENE MUTATION; GENE SEQUENCE; LETTER; MAMMAL CELL; MOLECULAR BIOLOGY; MONKEY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN STABILITY; PROTEIN SYNTHESIS; WILD TYPE;

EID: 0036146023     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1612963     Document Type: Letter

References (4)

1. Protein S deficiency: A database of mutations - Summary of the first update
2. A quantitative protein S deficiency associated with a novel nonsense mutation and markedly reduced levels of mutated mRNA
3. Molecular basis of a hereditary type I protein S deficiency caused by a substitution of Cys for Arg474
4. Protein S secretion differences of missense mutants account for phenotypic heterogeneity