Tracking the cognitive pharmacodynamics of psychoactive substances with combinations of behavioral and neurophysiological measures

Neuropsychopharmacology

Volumn 26, Issue 1, 2002, Pages 27-39

  Gevins, Alan ^a,b   Smith, Michael E ^a   McEvoy, Linda K ^a  

^a San Francisco Brain Research Institute and SAM Technology   (United States)

^b SFBRI   (United States)

Author keywords

Alcohol; Attention; Caffeine; Cognition; Diphenhydramine; EEG; Event related potentials; Multivariate pattern recognition; Pharmacodynamics; Working memory

Indexed keywords

ALCOHOL; CAFFEINE; DIPHENHYDRAMINE;

ADULT; ARTICLE; BEHAVIOR; COGNITION; CONTROLLED STUDY; DRUG DETERMINATION; DRUG EFFECT; ELECTROENCEPHALOGRAM; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MENTAL FUNCTION; MENTAL HEALTH; MULTIVARIATE ANALYSIS; NEUROPHYSIOLOGY; NORMAL HUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; WORKING MEMORY;

EID: 0036145429     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(01)00300-1     Document Type: Article

References (62)

1. Subjective and objective sleepiness in the active individual
2. Performance and evoked potential measures of various states of daytime sleepiness
3. The psychopharmacological and electrophysiological effects of single doses of caffeine in healthy human subjects
4. The effects of ethanol on EEG activity in males at risk for alcoholism
5. Human brain potentials during the onset of sleep
6. The effects of alcohol upon the electroencephalogram (brain waves)
7. Effects of moderate and high doses of alcohol on attention, impulsivity, discriminability, and response bias in immediate and delayed recall performance
8. Ocular artifact reduction by adaptive filtering
9. Effects of caffeine or diphenhydramine on visual vigilance
10. Effects of caffeine or diphenhydramine on visual vigilance
11. Treatment of allergic rhinitis: Effect on occupation productivity and work force costs
12. Changes in the EEG as the subject learns to recall
13. Effects of task difficulty on EEG measures of cerebral engagement
14. The pharmacodynamics of diphenhydramine-induced drowsiness and changes in mental performance
15. Quantitative effects of cetirizine and diphenhydramine on mental performance measured using an automobile driving simulator
16. Detecting transient cognitive impairment with EEG pattern recognition methods
17. Neurophysiological measures of working memory and individual differences in cognitive ability and cognitive style
18. Monitoring working memory load during computer-based tasks with EEG pattern recognition methods
19. High resolution EEG mapping of cortical activation related to working memory: Effects of task difficulty, type of processing, and practice
20. High resolution evoked potential imaging of the cortical dynamics of human working memory
21. Differentiating the effects of three benzodiazepines on non-REM sleep EEG spectra
22. Computer rejection of EEG artifact. II: Contamination by drowsiness
23. EEG alterations in patients treated with clozapine in relation to plasma levels
24. Development and critical evaluation of an objective procedure for the electroencephalographic classification of psychotropic drugs
25. Quantification of sleepiness: A new approach
26. EEG characteristics of frontal midline theta activity
27. Effects of caffeine on simple reaction time and movement time
28. Does caffeine intake enhance absolute levels of cognitive performance?
29. Initial and steady-state effects of diphenhydramine and loratadine on sedation, cognition, mood, and psychomotor performance
30. Alcohol and vigilance performance: A review
31. Caffeine effects on perceptual and motor processes
32. Influence of caffeine on information stages in well rested and fatigued subjects
33. Influence of caffeine on selective attention in well rested and fatigued subjects
34. Acute effects of caffeine on selective attention and visual search processes
35. EEG alpha activity increases during transient episodes of ethanol-induced euphoria
36. Changes in alertness are a principal component of variance in the EEG spectrum
37. A method for assessing alertness fluctuations in vigilance and the EEG spectrum
38. Dynamic cortical networks of verbal and spatial working memory: Effects of memory load and task practice
39. Test-retest reliability of cognitive EEG
40. Long term observation on Fm-theta during mental effort
41. Effects of terfenadine, diphenhydramine, and placebo on skills performance
42. Pharmacologically induced changes in arousal: Effects on behavioral and electrophysiologic measures of alertness and attention
43. Alertness and attention: Basic science and electrophysiologic correlates
44. Behavioral toxicity of medicinal drugs. Practical consequences, incidence, management and avoidance
45. The effects of Benadryl and Hismanal on psychomotor performance and perceived performance
46. Alcohol intoxication reduces visual sustained attention
47. Pharmacokinetic and dynamic studies with a new anxiolytic, suriclone, utlizing EEG mapping and psychometry
48. Test-retest reliability in EEG frequency analysis
49. The use of diurnal vigilance changes in the EEG to verify vigilance-enhancing effects of memantine in a clinical pharmacological study
50. Cognitive psychophysiology in nootropic drug research: Effects of Ginkgo biloba on event-related potentials (P300) in age-associated memory impairment
51. Neurophysiological indices of strategy development and skill acquisition
52. Benzodiazepine-induced persisting amnestic disorder: Are older adults at risk?
53. Antihistamine effects on the central nervous system, cognitive performance, and subjective states
54. Extreme sleepiness: Quantification of EOG and spectral EEG parameters
55. Mood and cognitive side effects of interferon-αtherapy
56. Impairment of cognitive function in women receiving adjuvant treatment for high-risk breast cancer: High does-versus standard-dose chemotherapy
57. Cognitive side-effects of chronic antiepileptic drug treatment: A review of 25 years of research
58. Analytic methods to differentiate similar electroencephalographic spectra: Neural networkj and discriminant analysis
59. Effects of fexofenadine, diphenhydramine, and alcohol on driving performance. A randomized, placebo-controlled trial in the Iowa driving simulator
60. Characterization of daytime sleepiness and psychomotor performance following H1 receptor antagonists