Galanin receptor antagonists decrease fat preference in Brattleboro rat

Neuropharmacology

Volumn 42, Issue 1, 2002, Pages 134-141

  Odorizzi, M ^a   Fernette, B ^a   Angel, E ^a   Burlet, C ^a   Tankosic, P ^a   Burlet, A ^a,b  

^a INSERM   (France)

^b SNCI   (France)

Author keywords

Diabetes insipidus; Feeding; Galanin mRNA; Neuropeptide; Nutrient selection

Indexed keywords

C 7; FAT; GALANIN; GALANIN DERIVATIVE; GALANIN RECEPTOR; GALANIN[1-13]SPANTIDE AMIDE; GALANTIDE; M 15; MESSENGER RNA; RECEPTOR BLOCKING AGENT; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN VENTRICLE; CONTROLLED STUDY; DRUG EFFECT; FAT INTAKE; FOOD PREFERENCE; GENE OVEREXPRESSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; THALAMUS MIDLINE NUCLEUS;

ANIMALS; DIETARY FATS; FOOD PREFERENCES; GALANIN; HYPOTHALAMUS; IN SITU HYBRIDIZATION; INJECTIONS, INTRAVENTRICULAR; MALE; PEPTIDE FRAGMENTS; RATS; RATS, BRATTLEBORO; RECEPTORS, GALANIN; RECEPTORS, NEUROPEPTIDE; RNA, MESSENGER; SUBSTANCE P;

EID: 0036141534     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(01)00115-0     Document Type: Article

References (33)

1. Galanin-containing neurons in the paraventricular nucleus: A neurochemical marker for fat ingestion and body weight gain
2. Ingestive behaviors of the rat deficient in vasopressin synthesis (Brattleboro strain). Effect of chronic treatment by dDAVP
3. Galanin antagonists block galanin-induced feeding in the hypothalamus and amygdala of the rat
4. Galanin and the galanin antagonist M40 do not change fat intake in a fat-chow choice paradigm in rats
5. Galanin receptor antagonists M40 and C7 block galanin induced feeding
6. Cloning, pharmacological characterization and distribution of a novel galanin receptor
7. Paraventricular area: Critical focus of a longitudinal neurocircuitry mediating food intake
8. Distribution of a rat galanin receptor mRNA in rat brain
9. Diurnal rhythm of neuropeptide Y-like immunoreactivity in the suprachiasmatic, arcuate and paraventricular nuclei and other hypothalamic sites
10. Vasopressin-deficient paraventricular magnocellular neurons of homozygous Brattleboro rats synthesize neuropeptide Y
11. Aqueduct occlusion does not impair feeding induced by either third or fourth ventricle galanin injection
12. Galanin injection into the nucleus of the solitary tract stimulates feeing in rats with lesions of the paraventricular nucleus of th hypothalamus
13. Galanin-R1 receptor mRNA expression in the hypothalamus of the Brattleboro rat
14. Neurochemical-neuroendocrine systems in the brain controlling macronutrient intake and metabolism
15. Impact of a galanin antagonist on exogenous galanin and natural patterns of fat ingestion
16. The novel high affinity antagonist, galantide, blocks the galanin mediated inhibition of glucose-induced insulin secretion
17. Hypothalamic neuropeptides could mediate the anorectic effects of fenfluramine
18. Semiquantitative distribution of galanin receptor (GAL-R1) mRNA-containing cells in the male rat hypothalamus
19. Expression of the galanin receptor subtype Gal-R2 mRNA in the rat hypothalamus
20. Effect of neuropeptide Y on ingestive behaviors in the rat
21. The Brattleboro magnocellular neurosecretory system: A model for the study of peptidergic neurons
22. Dietary preferences of Brattleboro rat correlated with an overexpression of galanin in the hypothalamus
23. Galanin coexists with vasopressin in the normal rat hypothalamus and galanin's synthesis is increased in the Brattleboro (diabetes insipidus) rat
24. Effects of galanin on food intake in rats; involvement of lateral and ventro-median hypothalamic sites
25. Single base deletion in the vasopressin gene is the cause of diabetes insipidus in Brattleboro rats
26. Effects of dietary preference and galanin administration in the paraventricular or amygdaloid nucleus on diet self-selection
27. Differential effects of baseline macronutrient preferences on macronutrient selection after galanin, NPY and an overnight fast
28. Paraventricular nucleus injections of peptide YY and neuropeptide Y preferentially enhance carbohydrate ingestion
29. K(+)-stimulated neuropeptide Y release into the paraventricular nucleus and relation to feeding behavior in free-moving rats
30. Effects of PVN galanin on macronutrient selection
31. The discovery of the Brattleboro rat, recommended nomenclature and the questions of proper controls
32. Isolation and characterization of a complementary DNA (galanin) clone from estrogen-induced pituitary tumor messenger RNA
33. Immunotargeted lesions of paraventricular CRF and AVP neurons in developing rats reveal the pattern of maturation of these systems and their functional importance