Microsatellite instability in colorectal cancer: Prognostic, predictive or both?

American Journal of Pathology

Volumn 160, Issue 1, 2002, Pages 384-386

  Van Rijnsoever, Marius ^a   Elsaleh, Hany ^a   Iacopetta, Barry ^a   Guidoboni, Massimo ^b   Viel, Alessandra ^b   Del Tin, Laura ^b   Boiocchi, Mauro ^b   Dolcetti, Riccardo ^b   Gafa, Roberta ^c   Lanza, Giovanni ^c   Doglioni, Claudio ^d   Macri, Ettore ^d   Russo, Antonio ^e   Santini, Alessandra ^f  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

^c UNIVERSITY OF FERRARA   (Italy)

^d Department of Pathology   (Italy)

^e CANCER RESEARCH AND PREVENTION INSTITUTE ISPO   (Italy)

^f UNIVERSITY HOSPITAL OF FERRARA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER SURVIVAL; COLORECTAL CANCER; CYTOTOXIC T LYMPHOCYTE; HUMAN; LETTER; LYMPHOCYTE COUNT; MICROSATELLITE INSTABILITY; PRIORITY JOURNAL; PROGNOSIS;

EID: 0036141203     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64383-0     Document Type: Letter

References (20)

1. M Guidoboni R Gafa A Viel C Doglioni A Russo A Santini L Del Tin E Macri G Lanza M Boiocchi R Dolcetti Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis Am J Pathol 159 2001 297 304
2. R Gryfe H Kim ET Hsieh MD Aronson EJ Holowaty SB Bull M Redston S Gallinger Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer N Engl J Med 342 2000 69 77
3. A Hemminki JP Mecklin H Jarvinen LA Aaltonen H Joensuu Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy Gastroenterology 119 2000 921 928
4. CM Wright OF Dent M Barker RC Newland PH Chapuis EL Bokey JP Young BA Leggett JR Jass GA Macdonald Prognostic significance of extensive microsatellite instability in sporadically clniicopathological stage C colorectal cancer Br J Surg 87 2000 1197 1202
5. KM Feeley JF Fullard MA Heneghan T Smith M Maher RP Murphy TA O'Gorman Microsatellite instability in sporadic colorectal carcinoma is not an indicator of prognosis J Pathol 188 1999 14 17
6. S Salahshor U Kressner H Fischer G Lindmark B Climelius L Pahlman A Lindblom Microsatellite instability in sporadic colorectal cancer is not an independent prognostic factor Br J Cancer 81 1999 190 193
7. H Elsaleh D Joseph F Grieu N Zeps N Spry B Iacopetta Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer Lancet 355 2000 1745 1750
8. H Elsaleh B Powell K McCaul F Grieu R Grant D Joseph B Iacopetta p53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma Clin Cancer Res 7 2001 1343 1349
9. DJ Ahnen P Feigl G Quan C Fenoglio-Preiser LC Lovato PA Bunn Jr G Stemmerman JD Wells JS Macdonald FL Meyskens Jr Ki-ras mutation and p53 overexpression predict the clinical behavior of colorectal cancer: a Southwest Oncology Group study Cancer Res 58 1998 1149 1158
10. J Breivik RA Lotte GI Meling TO Rognum AL Borresen-Dale G Gaudernack Different genetic pathways to proximal and distal colorectal cancer influenced by sex-related factors Int J Cancer 74 1997 664 669
11. KM Feeley JF Fullard MA Heneghan T Smith M Maher RP Murphy TA O'Gorman Microsatellite instability in sporadic colorectal carcinoma is not an indicator of prognosis J Pathol 188 1999 14 17
12. S Salahshor U Kressner H Fischer G Lindmark B Climelius L Pahlman A Lindblom Microsatellite instability in sporadic colorectal cancer is not an independent prognostic factor Br J Cancer 81 1999 190 193
13. CM Wright OF Dent M Barker RC Newland PH Chapuis EL Bokey JP Young BA Leggett JR Jass GA Macdonald Prognostic significance of extensive microsatellite instability in sporadically clniicopathological stage C colorectal cancer Br J Surg 87 2000 1197 1202
14. KC Halling AJ French SK McDonnell LJ Burgart DJ Schaid BJ Peterson L Moon-Tasson MR Mahoney DJ Sargent MJ O'Connell TE Witzig GH Farr Jr RM Goldberg SN Thibodeau Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers J Natl Cancer Inst 91 1999 1295 1303
15. R Gryfe H Kim ET Hsieh MD Aronson EJ Holowaty SB Bull M Redston S Gallinger Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer N Engl J Med 342 2000 69 77
16. M Guidoboni R Gafa A Viel C Doglioni A Russo A Santini L Del Tin E Macri G Lanza M Boiocchi R Dolcetti Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis Am J Pathol 159 2001 297 304
17. A Hemminki JP Mecklin H Jarvinen LA Aaltonen H Joensuu Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy Gastroenterology 119 2000 921 928
18. H Elsaleh D Joseph F Grieu N Zeps N Spry B Iacopetta Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer Lancet 355 2000 1745 1750
19. PH Nichols U Ward CW Ramsden JN Primrose The effect of 5-fluorouracil and alpha interferon and 5-fluorouracil and leucovorin on cellular anti-tumour immune responses in patients with advanced colorectal cancer Br J Cancer 70 1994 946 949
20. R Zagozdzon J Golab Immunomodulation by anticancer chemotherapy: more is not always better (review) Int J Oncol 18 2001 417 424