Prophylactic Intravenous Use of Milrinone After Cardiac Operation in Pediatrics (PRIMACORP) study

American Heart Journal

Volumn 143, Issue 1, 2002, Pages 15-21

  Hoffman, Timothy M ^a   Wernovsky, Gil ^a   Atz, Andrew M ^b   Bailey, James M ^c   Akbary, Akbar ^d   Kocsis, John F ^d   Nelson, David P ^e   Chang, Anthony C ^h   Kulik, Thomas J ^f   Spray, Thomas L ^a   Wessel, David L ^g  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Sanofi Synthelabo Inc   (United Kingdom)

^e CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^f UNIVERSITY OF MICHIGAN HOSPITALS   (United States)

^g BOSTON CHILDREN S HOSPITAL   (United States)

^h NONE

Author keywords

[No Author keywords available]

Indexed keywords

MILRINONE; PLACEBO;

ARTICLE; BOLUS INJECTION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEATH; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; FEMALE; FORWARD HEART FAILURE; HEART INDEX; HEART SURGERY; HIGH RISK PATIENT; HUMAN; MALE; MULTICENTER STUDY; PEDIATRIC SURGERY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROPHYLAXIS; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; STATISTICAL ANALYSIS;

EID: 0036141173     PISSN: 00028703     EISSN: None     Source Type: Journal    
DOI: 10.1067/mhj.2002.120305     Document Type: Article

References (27)

1. Congenital heart disease in infancy and childhood
2. Medical management of the patient undergoing cardiac surgery
3. Cardiac performance and mortality early after intracordiac surgery in infants and young children
4. Myocardiol performance after repair of congenital cardiac defects in infants and children: Response to volume loading
5. Effect of hemofiltrated whole blood pump priming on hemodynamics and respiratory function after the arterial switch operation in neonates
6. Postoperative course and hemodynamic profile after the arterial switch operation in neonates and infants: A comparison of low-flow cardiopulmonary bypass and circulatory arrest
7. Delayed impairment of cerebral oxygenation after deep hypothermic circulatory arrest in children
8. Perioperative effects of alpha-stat versus pH-stat strategies for deep hypothermic cardiopulmonary bypass in infants
9. Serial blood lactate measurements predict early outcome after neonotal repair or palliation for complex congenital heart disease
10. Milrinone in the treatment of low output states following cardiac surgery
11. Pharmocokinetics and side effects of milrinone in infants and children after open heart surgery
12. Milrinone: Systemic and pulmonary hemodynamic effects in neonates after cardiac surgery
13. The pharmacokinetics of milrinone in pediatric patients after cardiac surgery
14. Effects of cardiopulmonary bypass on leukocyte and endothelial adhesion molecules
15. Intravenous milrinone following cardiac surgery, 1: Effects of bolus infusion followed by variable dose maintenance infusion
16. Primacor
17. Effects of milrinone on coronary hemodynamics and myocardial energetics in patients with congestive heart failure
18. A multiple testing procedure for clinical trials
19. Discrete sequential boundaries for clinical trials
20. Effect of oral milrinone on mortality in severe chronic heart failure
21. Efficacy and safety of sustained (48 hour) intravenous infusions of milrinone in patients with severe congestive heart failure: A multicenter study
22. Effect of milrinone on postbypass pulmonary hypertension in children after tetralogy of Fallot repair
23. Hemodynamic effects of iv milrinone lactate in pediatric patients with septic shock: A prospective, double-blinded, randomized, placebo- controlled, interventional study
24. Pharmacokinetics and pharmacodynamics of milrinone lactate in pediatric patients with septic shock
25. Validation of relative value scale for congenital heart operations
26. The Society of Thoracic Surgeons National Congenital Heart Surgery Database Report: Analysis of the first harvest (1994-1997)