Obstructive apnea during sleep is associated with peripheral vasoconstriction

American Journal of Respiratory and Critical Care Medicine

Volumn 165, Issue 1, 2002, Pages 61-66

  Imadojemu, Virginia A ^a,b   Gleeson, Kevin ^a,b   Gray, Kristen S ^a,b   Sinoway, Lawrence I ^a,b   Leuenberger, Urs A ^a,b  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Blood flow; Blood pressure; Doppler; Muscle sympathetic nervous system; Obstructive sleep apnea; Vasoconstriction

Indexed keywords

ADULT; AGED; ARTICLE; BLOOD FLOW VELOCITY; BLOOD PRESSURE; BREATH HOLDING; CLINICAL ARTICLE; DISEASE ASSOCIATION; FACE MASK; FEMALE; HUMAN; HYPOXIA; MALE; MEAN ARTERIAL PRESSURE; OXYGEN THERAPY; PATHOGENESIS; PRIORITY JOURNAL; SLEEP; SLEEP APNEA SYNDROME; SYMPATHETIC TONE; VASCULAR RESISTANCE; VASOCONSTRICTION; WAKEFULNESS;

EID: 0036140888     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.165.1.2009062     Document Type: Article

References (35)

1. The sleep apnea syndromes
2. Cardiopulmonary consequences of obstructive sleep apnea
3. Hemodynamic consequences of obstructive sleep apnea
4. Is high and fluctuating muscle nerve sympathetic activity in the sleep apnoea syndrome of pathogenetic importance for the development of hypertension?
5. Surges of muscle sympathetic nerve activity during obstructive apnea are linked to hypoxemia
6. Sympathetic neural mechanisms in obstructive sleep apnea
7. Obstructive sleep apnea and cardiac index
8. Stroke volume and cardiac output decrease at termination of obstructive apneas
9. Cardiovascular changes associated with obstructive sleep apnea syndrome
10. Comparison of finger and intra-arterial blood pressure monitoring at rest and during laboratory testing
11. Sympathetic and blood pressure responses to voluntary apnea are augmented by hypoxemia
12. Somatosensory, proprioceptive and sympathetic activity in human peripheral nerves
13. Contribution of perfusion pressure to vascular resistance response during head-up tilt
14. Hypoxia augments apnea-induced peripheral vasoconstriction in humans
15. Time course and magnitude of blood flow changes in the human quadriceps muscles during and following rhythmic exercise
16. Laser-Doppler measurement of skin blood flow: Comparison with plethysmography
17. Norepinephrine clearance is increased during acute hypoxemia in humans
18. Indications and standards for Cardiopulmonary sleep studies
19. Neurocirculatory consequences of abrupt change in sleep state in humans
20. Neurocirculatory consequences of negative intrathoracic pressure vs. asphyxia during voluntary apnea
21. Periodic, profound peripheral vasoconstriction - A new marker of obstructive sleep apnea
22. The cutaneous circulation
23. The effects of oxygen in patients with sleep apnea
24. Constrasting effects of hypoxia and hypercapnia on ventilation and sympathetic activity in humans
25. Hemodynamic studies in sleep apnea
26. Gas exchange and hemodynamics during sleep
27. Comparative hemodynamic effects of periodic obstructive and simulated central apneas in sedated pigs
28. Cellular mechanisms involved in the vascular myogenie response
29. Myogenic effects enhance norepinephrine construction: Inhibition by nitric oxide and felodipine
30. A specific and potent pressor effect of hypoxia in patients with sleep apnea
31. Patients with obstructive sleep apnea have an abnormal peripheral vascular response to hypoxia
32. Sympathetic muscle nerve activity during sleep in man
33. Neural mechanism of the pressor response to obstructive and nonobstructive apnea
34. Sympathetic-nerve activity during sleep in normal subjects