Rapid liquid chromatography-tandem mass spectrometry method for routine analysis of cyclosporin A over an extended concentration range

Clinical Chemistry

Volumn 48, Issue 1, 2002, Pages 69-76

  Keevil, B G ^a   Tierney, D P ^a   Cooper, D P ^a   Morris, M R ^a  

^a WYTHENSHAWE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONITRILE; AMMONIUM ACETATE; ASCOMYCIN; CYCLOSPORIN A; FORMIC ACID;

ARTICLE; CALIBRATION; CONTROLLED STUDY; DEVICE; DRUG DETERMINATION; HEART LUNG TRANSPLANTATION; HUMAN; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; PRECIPITATION; PROTEIN ANALYSIS; SAMPLING; SENSITIVITY AND SPECIFICITY; STANDARD; STATISTICAL ANALYSIS; TANDEM MASS SPECTROMETRY;

EID: 0036140448     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/48.1.69     Document Type: Article

References (21)

1. Critical issues in cyclosporine monitoring: Report of the Task Force on Cyclosporine Monitoring
2. Lake Louise Consensus Conference on Cyclosporin Monitoring in Organ Transplantation: Report of the consensus panel
3. Clinical aspects of cyclosporin nephrotoxicity
4. Cyclosporin whole blood immunoassays (AxSYM, CEDIA, and Emit): A critical overview of performance characteristics and comparison with HPLC
5. Performance and specificity of monoclonal immunoassays for cyclosporin monitoring: How specific is specific?
6. Is 3-hour cyclosporine blood level superior to trough level in early post-renal transplantation period?
7. Neoral monitoring by simplified sparse sampling area under the concentration-time curve
8. Two-hour cyclosporine level determination is the appropriate tool to monitor Neoral therapy
9. Cyclosporine monitoring in renal transplantation: Area under the curve monitoring is superior to trough-level monitoring
10. Screening for medium chain acyl-CoA dehydrogenase deficiency using electrospray ionisation tandem mass spectrometry
11. Screening blood spots for inborn errors of metabolism by electrospray tandem mass spectrometry with a microplate batch process and a computer algorithm for automated of abnormal profiles
12. A specific method for the measurement of cyclosporin A in human whole blood by liquid chromatography-tandem mass spectrometry
13. Microscale high performance liquid chromatography-electrospray mass spectrometry assay for cyclosporin A in blood
14. Sensitive, specific quantitative analysis of tacrolimus (FK506) in blood by liquid chromatography-electrospray tandem mass spectrometry
15. Simultaneous on-line extraction and analysis of sirolimus (rapamycin) and cyclosporin in blood by liquid chromatography-electrospray mass spectrometry
16. Simultaneous quantification of cyclosporin A and its major metabolites by time-of-flight secondary-ion mass spectrometry and matrix-assisted laser desorption/ionization mass spectrometry utilizing data analysis techniques: Comparison with high-performance liquid chromatography
17. Quantitative measurement of cyclosporin A in blood by time-of-flight mass spectrometry
18. Thermospray high-performance liquid chromatography/mass spectrometric determination of cyclosporins
19. New approaches to cyclosporine monitoring raise further concerns about analytical techniques
20. Validation of an assay for routine monitoring of sirolimus using HPLC with mass spectrometric detection
21. Automated simultaneous quantification of immunosuppressants 40-O-(2-hydroxyethyl)rapamycin and cyclosporine in blood with electrospray-mass spectrometric detection