Immunogenicity and protective efficacy of replication-incompetent influenza virus-like particles

Journal of Virology

Volumn 76, Issue 2, 2002, Pages 767-773

  Watanabe, T ^a   Watanabe, S ^a   Neumann, G ^a   Kida, H ^a   Kawaoka, Y ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMAGGLUTININ; INFLUENZA VACCINE; NUCLEOPROTEIN; SIALIDASE; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOGENICITY; INFLUENZA VIRUS; KNOCKOUT GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VACCINATION; VIRUS PARTICLE; VIRUS REPLICATION;

ANIMALS; ANTIBODIES, VIRAL; BODY WEIGHT; CELL LINE; CHICK EMBRYO; DNA, RECOMBINANT; DOGS; FEMALE; GENE DELETION; GENES, VIRAL; HUMANS; INFLUENZA VACCINES; INFLUENZA, HUMAN; LETHAL DOSE 50; MICE; MICE, INBRED BALB C; ORTHOMYXOVIRIDAE; SURVIVAL RATE; TIME FACTORS; VACCINATION; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 0036139062     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.76.2.767-773.2002     Document Type: Article

References (24)

1. The efficacy of live attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine in children
2. Genotypic stability of cold-adapted influenza virus vaccine in an efficacy clinical trial
3. Influenza virus NS1 protein enhances the rate of translation initiation of viral mRNAs
4. Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system
5. A randomized controlled trial of cold-adapted and inactivated vaccines for the prevention of influenza A disease
6. Influenza virus NS1 protein stimulates translation of the M1 protein
7. Characterization of influenza virus NS1 protein by using a novel helper-virus-free reverse genetic system
8. Rescue of influenza A virus from recombinant DNA
9. Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems
10. Molecular and biological changes in the cold-adapted "master strain" A/AA/6/60 (H2N2) influenza virus
11. Biological activity of monoclonal antibodies to operationally defined antigenic regions on the hemagglutinin molecule of A/Seal/Massachusetts/1/80 (H7N7) influenza virus
12. Mapping of the two overlapping genes for polypeptides NS1 and NS2 on RNA segment 8 of influenza virus genome
13. + responses in mice
14. Orthomyxoviruses
15. Nuclear import and export of influenza virus nucleoprotein
16. Influenza A virus NS2 protein mediates vRNP nuclear export through NES-independent interaction with hCRM1
17. Generation of influenza A viruses entirely from cloned cDNAs
18. Plasmid-driven formation of influenza virus-like particles
19. The influenza virus NEP (NS2 protein) mediates the nuclear export of viral ribonucleoproteins
20. Translational control by influenza virus. Identification of cis-acting sequences and trans-acting factors which may regulate selective viral mRNA translation
21. Transfectant influenza A viruses are effective recombinant immunogens in the treatment of experimental cancer
22. A chimeric influenza virus expressing an epitope of outer membrane protein F of Pseudomonas aeruginosa affords protecion against challenge with P. aeruginosa in a murine model of chronic pulmonary infection
23. Efficient expression of the tumor-associated antigen MAGE-3 in human dendritic cells, using an avian influenza virus vector
24. Membrane-anchored incorporation of a foreign protein in recombinant influenza virions