Estimation of p-values for global alignments of protein sequences

Bioinformatics

Volumn 17, Issue 12, 2002, Pages 1158-1167

  Webber, Caleb ^a   Barton, Geoffrey J ^a,b  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN;

ALGORITHM; AMINO ACID SEQUENCE; ANALYTICAL ERROR; ARTICLE; CALCULATION; COMPUTER PROGRAM; CONTROLLED STUDY; PRIORITY JOURNAL; PROBABILITY; PROTEIN FAMILY; PROTEIN FOLDING; SCORING SYSTEM; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; STATISTICAL ANALYSIS;

EID: 0036138287     PISSN: 13674803     EISSN: 13674811     Source Type: Journal    
DOI: 10.1093/bioinformatics/17.12.1158     Document Type: Article

References (38)

1. Amino acid substitution matrices from an information theoretic perspective
2. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
3. The estimation of statistical parameters for local alignment score distributions
4. InterPro-an integrated documentation resource for protein families, domains and functional sites
5. The EMBL nucleotide sequence database
6. Protein multiple sequence alignment and flexible pattern matching
7. An efficient algorithm to locate all locally optimal alignments between two sequences allowing for gaps
8. Protein sequence alignment techniques
9. Evaluation and improvements in the automatic alignment of protein sequences
10. A strategy for the rapid multiple alignment of protein sequences: Confidence levels from tertiary structure comparisons
11. Flexible protein sequence patterns-a sensitive method to detect weak structural similarities
12. The Pfam protein families database
13. The Protein Data Bank: A computer based archival file for macromolecular structures
14. Assessing sequence comparison methods with reliable structurally identified distant evolutionary relationships
15. The significance of protein sequence similarities
16. A Model of evolutionary change in proteins. Matrices for detecting distant relationships
17. Aligning amino acid sequences: Comparison of commonly used methods
18. Exhaustive matching of the entire protein sequence database
19. Profile analysis: Detection of distantly related proteins
20. Amino acid substitution matrices from protein blocks
21. Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes
22. Accurate formula for P-values of gapped local sequence and profile alignments
23. SCOP: A structural classification of proteins database for the investigation of sequences and structures
24. A general method applicable to the search for similarities in the amino acid sequence of two proteins
25. RSDB: Representative protein sequence databases have high information content
26. Comparison of methods for searching protein sequence databases
27. Empirical statistical estimates for sequence similarity searches
28. Measurement and significance of protein structural similarity
29. A strategy for the evaluation of protein sequence alignments: Datasets and quality measures
30. Identification of common molecular subsequences
31. Pfam: A comprehensive database of protein domain families based on seed alignments
32. Local protein similarity does not imply a structural relationship