Intracellular trafficking of a tagged and functional mammalian olfactory receptor

Journal of Neurobiology

Volumn 50, Issue 1, 2002, Pages 56-68

  Ivic, Lidija ^a   Zhang, Cen ^a   Zhang, Xinmin ^a   Yoon, Sung Ok ^b   Firestein, Stuart ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Calcium imaging; Fusion; Green fluorescent protein; Olfactory sensory neurons; Plasma membrane targeting

Indexed keywords

EPITOPE; FLAG I7 ADV FUSION PROTEIN; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; I7 EGFP ADV FUSION PROTEIN; UNCLASSIFIED DRUG; VIRUS VECTOR;

ADENOVIRUS; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CARBOXY TERMINAL SEQUENCE; GENE CONSTRUCT; GENE TRANSFER; INTRACELLULAR TRANSPORT; LIGAND BINDING; NEUROANATOMY; NONHUMAN; OLFACTOMETRY; OLFACTORY EPITHELIUM; OLFACTORY RECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN TARGETING; RAT; RECEPTIVE FIELD; RECEPTOR GENE; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; VIRUS RECOMBINANT;

ADENOVIRIDAE INFECTIONS; ANIMALS; CALCIUM SIGNALING; CELL LINE; CELL MEMBRANE; ELECTROOCULOGRAPHY; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; GTP-BINDING PROTEINS; HUMANS; LUMINESCENT PROTEINS; NEURONS; OLFACTORY MUCOSA; OLFACTORY PATHWAYS; OLFACTORY RECEPTOR NEURONS; RATS; RECEPTORS, CELL SURFACE; RECOMBINANT FUSION PROTEINS; TRANSFECTION;

EID: 0036136438     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/neu.10016     Document Type: Article

References (25)

1. The molecular receptive range of an odorant receptor
2. Odor-induced phosphorylation of olfactory cilia proteins
3. A novel multigene family may encode odorant receptors: A molecular basis for odor recognition
4. Activation of the sensory current in salamander olfactory receptor neurons depends on a G-protein mediated cAMP second messenger system
5. Olfactory receptor proteins - Expression, characterization and partial purification
6. Olfactory receptor trafficking involves conserved regulatory steps
7. Truncation releases olfactory receptors from the endoplasmic reticulum of heterologous cells
8. Construction of adenovirus vectors through Crelox recombination
9. A simplified system for generating recombinant adenoviruses
10. Efficient adenoviral vector-directed expression of a foreign gene to neurons and sustentacular cells in the mouse olfactory neuroepithelium
11. Distribution of putative odour receptor proteins in olfactory epithelium
12. Identification of ligands for olfactory receptors by functional expression of a receptor library
13. Probing olfactory receptors with sequence-specific antibodies
14. Functional expression of olfactory-adrenergic receptor chimeras and intracellular retention of heterologously expressed olfactory receptors
15. Putative odour receptors localize in cilia of olfactory receptor cells in rat and mouse: A freeze-substitution ultrastructural study
16. Molecular biology of odorant receptors in vertebrates
17. Seven-transmembrane proteins as odorant and chemosensory receptors
18. The variable and conserved interfaces of modeled olfactory receptor proteins
19. Sequence alignment of the G-protein coupled receptor superfamily
20. Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa
21. Functional identification and reconstitution of an odorant receptor in single olfactory neurons
22. A method for maintaining odor-responsive adult rat olfactory receptor neurons in short-term culture
23. Specificity and sensitivity of a human olfactory receptor functionally expressed in human embryonic kidney 293 cells and Xenopus Laevis oocytes
24. Functional expression of a mammalian odorant receptor
25. Adenovirus-mediated gene transfer in olfactory neurons in vivo