Comparative analysis of Prx1 and Prx2 expression in mice provides evidence for incomplete compensation

Anatomical Record

Volumn 266, Issue 1, 2002, Pages 1-4

  Chesterman, Elizabeth S ^a   Kern, Michael J ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Antibody; Bone; Cartilage; Development; Homeobox; Prx2; Transcription factor

Indexed keywords

HOMEODOMAIN PROTEIN; PROTEIN; PROTEIN PRX1; PROTEIN PRX2; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CRANIOFACIAL DEVELOPMENT; DEVELOPMENTAL GENETICS; EMBRYO; EMBRYO DEVELOPMENT; HOMEOBOX; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIMB DEVELOPMENT; MOUSE; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PRX1 GENE; PRX2 GENE; TRANSGENIC MOUSE;

ANIMALS; BLOTTING, WESTERN; EMBRYONIC AND FETAL DEVELOPMENT; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; HINDLIMB; IMMUNOHISTOCHEMISTRY; MICE; MYOCARDIUM; PEROXIDASES; SACCHAROMYCES CEREVISIAE PROTEINS; SKULL;

MUS MUSCULUS;

EID: 0036135728     PISSN: 0003276X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ar.10028     Document Type: Article

References (13)

1. Loss of function of the Prx1 and Prx2 homeobox genes alters architecture of the great elastic arteries and ductus arteriosus
2. Investigation of Prx1 protein expression provides evidence for conservation of cardiac-specific post-transcriptional regulation in vertebrates
3. The homeobox gene S8: Mesodermspecific expression in presomite embryos and in cells cultured in vitro and modulation in differentiating pluripotent cells
4. The expression pattern of the chick homeobox gene gMHox suggests a role in patterning of the limbs and face and in compartmentalization of somites
5. Expression patterns of the paired-related homeobox genes MHox/Prx1 and S8/Prx2 suggest roles in development of the heart and the forebrain
6. Prx-1 functions cooperatively with another paired-related homeobox gene, Prx-2, to maintain cell fates within the craniofacial mesenchyme
7. Paired-related homeobox genes cooperate in handplate and hindlimb zeugopod morphogenesis
8. The paired-like homeobox gene MHox is required for early events of skeletogenesis in multiple lineages
9. A chicken homeobox gene related to Drosophila paired is predominantly expressed in the developing limb
10. Identification of domains mediating transcription activation, repression, and inhibition in the paired related homeobox protein, Prx2 (S8)
11. The identification of Prx1 transcription regulatory domains provides a mechanism for unequal compensation by the Prx1 and Prx2 loci
12. The mouse homeobox gene, S8, is expressed during embryogenesis predominantly in mesenchyme
13. Prx1 and Prx2 in skeletogenesis: Roles in the craniofacial region, inner ear and limbs