Identification of N-myc regulatory regions involved in embryonic expression

Pediatric Research

Volumn 51, Issue 1, 2002, Pages 48-56

  Charron, J ^a   Gagnon, J F ^a   Cadrin Girard, J F ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EMBRYO DEVELOPMENT; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIMB BUD; MOUSE; NONHUMAN; ONCOGENE C MYB; PRIORITY JOURNAL; REPORTER GENE; TRANSGENIC MOUSE;

EID: 0036134665     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-200201000-00010     Document Type: Article

References (48)

1. The human myc gene family
2. Differentiation and apoptosis of neuroblastoma cells: Role of N-myc gene product
3. N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation
4. Myc target genes
5. Max: A helix- loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc
6. Use of transgenic mice to study myc family gene function in normal mammalian development and in cancer
7. Proteins of the Myc network: Essential regulators of cell growth and differentiation
8. N-Myc shares cellular functions with c-Myc
9. Expression and function of Myc family genes
10. N-myc gene amplification in rhabdomyosarcoma detected by fluorescence in situ hybridization: Its correlation with histologic features
11. Co-amplification of a novel gene, NAG, with the N-myc gene in neuroblastoma
12. Amplification of N-myc as a prognostic marker for patients with neuroblastoma
13. Human neuroblastoma cell lines that express N-myc without gene amplification
14. Genetic clinical markers of human neuroblastoma with special reference to N-myc oncogene: Amplified or not amplified? - An overview
15. Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene
16. Defects of embryonic organogenesis resulting from targeted disruption of the N-myc gene in the mouse
17. Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop
18. Defective development of the embryonic liver in N-myc-deficient mice
19. A targeted mutation reveals a role for N-myc in branching morphogenesis in the embryonic mouse lung
20. Defects in heart and lung development in compound heterozygotes for two different targeted mutations at the N-myc locus
21. Role of N-myc in the developing mouse kidney
22. A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice
23. Mutation of N-myc in mice: What does the phenotype tell us?
24. Dynamic expression pattern of the myc protooncogene in midgestation mouse embryos
25. Contrasting expression patterns of three members of the myc family of protooncogenes in the developing and adult mouse kidney
26. A comparative analysis of N-myc and c-myc expression and cellular proliferation in mouse organogenesis
27. Expression of the myc proto-oncogenes in developing human fetal brain
28. Tissue distribution of N-myc expression in the early organogenesis periods of the mouse embryo
29. Contrasting patterns of myc and N-myc expression during gastrulation of the mouse embryo
30. The N-myc proto-oncogene: Developmental expression and in vivo site-directed mutagenesis
31. N-myc proto-oncogene expression during organogenesis in the developing mouse as revealed by in situ hybridization
32. Transcriptional regulation of the N-myc gene: Identification of positive regulatory element and its double- and single-stranded DNA binding proteins
33. The upstream region of the mouse N-myc gene: Identification of an enhancer element that functions preferentially in neuroblastoma IMR32 cells
34. Localization of regulatory elements controlling human MYCN expression
35. Cell type-specific expression and negative regulation by retinoic acid of the human N-myc promoter in neuroblastoma cells
36. Loss of transcriptional attenuation in N-myc is associated with progression towards a more malignant phenotype
37. Differential regulation of the N-myc proto-oncogene by ROR alpha and RVR, two orphan members of the superfamily of nuclear hormone receptors
38. Definition of the human N-myc promoter region during development in a transgenic mouse model
39. A novel intron element operates posttranscriptionally to regulate human N-myc expression
40. Differential regulation of the N-myc gene in transfected cells and transgenic mice
41. Structure and expression of the murine N-myc gene
42. High-frequency disruption of the N-myc gene in embryonic stem and pre-B cell lines by homologous recombination
43. Preparative and analytical purification of DNA from agarose
44. Multiple cis-acting regulatory regions are required for restricted spatio-temporal Hoxa5 gene expression
45. Cell type-specific activity of the N-myc promoter in human neuroblastoma cells is mediated by a downstream silencer
46. The evolution of the vertebrates-genes and development
47. Cell type-specific activity of the N-myc promoter in human neuroblastoma cells is mediated by a downstream silencer