Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin in goats given enrofloxacin alone and in combination with probenecid

Veterinary Journal

Volumn 163, Issue 1, 2002, Pages 85-93

  Rao, G S ^a   Ramesh, S ^a   Ahmad, A H ^b   Tripathi, H C ^a   Sharma, L D ^b   Malik, J K ^a  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

^b G B PANT UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (India)

Author keywords

Ciprofloxacin; Enrofloxacin; Goats; Pharmacokinetics; Probenecid

Indexed keywords

CIPROFLOXACIN; ENROFLOXACIN; FLOXIDIN VET; PROBENECID; ANTI INFECTIVE AGENTS, FLUOROQUINOLONE; ANTINEOPLASTIC AGENT; QUINOLINE DERIVED ANTIINFECTIVE AGENT; QUINOLONE DERIVATIVE; URICOSURIC AGENT;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; COMPARTMENT MODEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG METABOLISM; DRUG POTENTIATION; FEMALE; GOAT; JUGULAR VEIN; MEAN RESIDENCE TIME; NONHUMAN; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TIME; ANIMAL; ANIMAL DISEASE; BLOOD; HALF LIFE TIME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAMUSCULAR DRUG ADMINISTRATION; METABOLISM;

CAPRA HIRCUS;

ANIMAL; ANTI-INFECTIVE AGENTS, FLUOROQUINOLONE; ANTINEOPLASTIC AGENTS; AREA UNDER CURVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIPROFLOXACIN; FEMALE; GOATS; HALF-LIFE; INJECTIONS, INTRAMUSCULAR; PROBENECID; QUINOLONES; SUPPORT, NON-U.S. GOV'T; URICOSURIC AGENTS;

EID: 0036133989     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1053/tvjl.2001.0594     Document Type: Article

References (32)

1. Adkison K. D.K. Artu A. A. Powers K. M. Shen D. D. Contribution of probenecid-sensitive anion transport processes at the brain capillary endothelium and choroid plexus to the efficient efflux of valproic acid from the central nervous system Journal of Pharmacology and Experimental Therapeutics 268 1994 797-805
2. Altreuther P. Data on chemistry and toxicology of Baytrill® Veterinary Medicine Reviews 2 1987 87-89
3. Anadon A. Martinez-larranaga M. R. Diaz M. J. Fernandez-cruz M. L. Martinez M. A. Frejo M. T. Martinez M. Iturbe J. Tafur M. Pharmacokinetic variables and tissue residues of enrofloxacin and ciprofloxacin in healthy pigs American Journal of Veterinary Research 60 1999 1377-1382
4. Baggot J. D. Principles of drug disposition in domestic animals The Basis of Veterinary Clinical Pharmacology 1977 W.B. Saunders Co. Philadelphia p. 144-189
5. Brown S.A. Fluoroquinolones in animal health Journal of Veterinary Pharmacology and Therapeutics 19 1996 1-14
6. Cabanes A. Margarita A. Josh M. Garcia A. Franscisca P. Pharmacokinetics of enrofloxacin after intravenous and intramuscular injection in rabbits American Journal of Veterinary Research 53 1992 2090-2093
7. Christensen J. M. Smith B. B. Murdane S. B. Hollingshead N. The disposition of five therapeutically important antimicrobial agents in ilamas Journal of Veterinary Pharmacology and Therapeutics 19 1996 431-438
8. Garcia O. H. Errecalde C. Prieto G. Luders C. Puelles I. Bercochea C. Fernandez C. Pharmacokinetics of enrofloxacin in calves Archivos de Medicina Veterinaria 28 1996 107-111
9. Garcia O. H. Gorla N. Luders C. Poloni G. Errecalde C. Prieto G. Puelles I. Comparative pharmacokinetics of enrofloxacin and ciprofloxacin in chickens Journal of Veterinary Pharmacology and Therapeutics 22 1999 209-212
10. Gibaldi M. Perrier D. Pharmacokinetics 1982 Marcel-Dekker Inc. New York
11. Intorre L. Mengozzi G. Bertini S. Begliacca M. Lichetti E. Soldani G. The plasma kinetics and tissue distribution of enrofloxacin and its metabolite, ciprofloxacin in the Muscovy Duck Veterinary Research Communications 21 1997 127-136
12. Jaehde H. Sorgel F. Reiter A. Sigl G. Naber K. G. Schunack W. Effect of probenecid on the distribution and elimination of ciprofloxacin in humans Clinical Pharmacology and Therapeutics 58 1995 532-541
13. Kaartinen L. Pam S. Pyörälä S. Pharmacokinetics of enrofloxacin in horses after single intravenous and intramuscular administra-tion Equine Veterinary Journal 29 1997a 378-381
14. Kaartinen L. Pyörälä S. Moilanen M. Raisanen S. Pharmacokinetics of enrofloxacin in newborn and one-week-old calves Journal of Veterinary Pharmacology and Therapeutics 20 1997b 470-482
15. Kaartinen L. Salonen M. Alli L. Pyörälä S. Pharmacokinetics of enrofloxacin after single intravenous, intramuscular and subcutaneous injections in lactating cows Journal of Veterinary Pharmacology and Therapeutics 9 1995 254-263
16. Kung K. L. Riond J.-L. Wanner M. Pharmacokinetics of enrofloxacin and its metabolite, ciprofloxacin after intravenous and oral administration of enrofloxacin in dogs Journal of Veterinary Pharmacology and Therapeutics 16 1993 462-468
17. Mengozzi G. Intorre L. Bertini S. Soldani G. Pharmacokinetics of enrofloxacin and its metabolite, ciprofloxacin after intravenous and intramuscular administration in sheep American Journal of Veterinary Research 57 1996 1040-1043
18. Neuman M. Comparative pharmacokinetic parameters of new systemic fluoroquinolones: a review Chemoterapia 6 1987 105-112
19. Nielsen P. Hansen N. G. Bioavailability of enrofloxacin after oral administration to fed and fasted pigs Pharmacology and Toxicology 80 1997 246-250
20. Nightingale C. H. Grant E. M. Quintiliani R. Pharmacodynamics and pharmacokinetics of levofloxacin Chemotherapy. 46 2000 6-14
21. Parikh V. Shivprakash Patel D. Gandhi T. P. Patel R. B. Santani D. D. Effect of aspirin on single and multiple dose pharmacokinetics of ciprofloxacin in rabbits Indian Journal of Pharmacology 28 1996 25-28
22. Pijpers A. Heinen E. Dejong A. Verheijden J. H.M. Enrofloxacin pharmacokinetics after intravenous and intramuscular administration in pigs Journal of Veterinary Pharmacology and Therapeutics 20 1997 42-43
23. Prescott J. F. Yielding K. M. In vitro susceptibility of selected veterinary bacterial pathogens to ciprofloxacin, enrofloxacin and norfloxacin Canadian Journal of Veterinary Research 54 1990 195-197
24. Sarasola P. Mckellar Q. A. Pharmacokinetics of bacampicillin in equids American Journal of Veterinary Research 56 1995 1486-1492
25. Scheer M. Studies on the antimicrobial activity of Baytril Veterinary Medicine Reviews 2 1987 90-99
26. Schroder J. Enrofloxacin: a new antimicrobial agent Journal of South African Veterinary Association 60 1989 122-124
27. Tyczkowska K. L. Hedeen K. M. Aucoin D. P. Aronson A. L. High performance liquid chromatographic method for the simultaneous determination of enrofloxacin and its primary metabolite ciprofloxacin in canine serum and prostatic tissue Journal of Chromatography 493 1989 337-346
28. Ulltrich K. J. Rumrich G. David C. Fritzsch G. Bisubstrates: substances that interact with both renal contraluminal organic anion and organic cation transport systems II: zwitterionic substrates Pflugers Archives 425 1993 300-312
29. Vancutsem P. M. Babish J. G. Schwark W. C. The Fluoroquinolone Antimicrobials: Structure, antimicrobial activity, pharmacokinetics, clinical use in domestic animals and toxicity Cornell Veterinarian 80 1990 173-186
30. Verma H. K. Pangawkar G. R. Chaudhary R. K. Srivastava A. K. Pharmacokinetics and dosage regimens of enrofloxacin in buffalo bulls after intramuscular administration Veterinary Research Communications 23 1999 501-505
31. Walker R.D. The use of fluoroquinolones for companion animal antimicrobial therapy Australian Veterinary Journal 78 2000 84-89
32. Zeng Z. Geng Q. Zeng Z. L. Feng Q. H. Pharmacokinetics and bioavailability of enrofloxacin in pigs Chinese Journal of Veterinary Sciences 16 1996 606-612