Assessment of positivity in immuno-assays with variability in background measurements: A new approach applied to the antibody response to Plasmodium falciparum MSP2

Journal of Immunological Methods

Volumn 259, Issue 1-2, 2002, Pages 111-118

  Irion, Andrea ^a   Beck, Hans Peter ^a   Smith, Tom ^a  

^a SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

Cutoff; ELISA; Latent class model; Malaria; Prevalence of positivity; Probability of positivity

Indexed keywords

MEROZOITE SURFACE PROTEIN 2; PROTEIN ANTIBODY;

ANTIBODY RESPONSE; ARTICLE; CALCULATION; DATA ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HYPOTHESIS; IMMUNE RESPONSE; LABORATORY TEST; MEROZOITE; PLASMODIUM FALCIPARUM; PREDICTION; PREVALENCE; PRIORITY JOURNAL; PROBABILITY; QUANTITATIVE ASSAY; RELIABILITY; SIMULATION; STATISTICAL MODEL; TANZANIA;

ANIMALS; ANTIBODIES, PROTOZOAN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FALSE POSITIVE REACTIONS; HUMANS; MALARIA, FALCIPARUM; MODELS, STATISTICAL; OBSERVER VARIATION; PLASMODIUM FALCIPARUM; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SEROLOGIC TESTS;

PLASMODIUM FALCIPARUM;

EID: 0036132643     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(01)00500-2     Document Type: Article

References (16)

1. The statistical analysis of data from immunoepidemiological studies
2. Latent class analysis permits unbiased estimates of the validity of DAT for the diagnosis of viceral leishmaniasis
3. Original antigenic sin, T cell memory, and malaria sporozoite immunity: A hypothesis for immune evasion
4. Essential flexibility in the T-cell recognition of antigen
5. The original sin of killer T cells
6. Immune evasion in malaria: Altered peptide ligands of the circumsporozoite protein
7. Random effects models in latent class analysis for evaluating accuracy of diagnostic tests
8. Logistic regression and latent class models for estimating positivities in diagnostic assays with poor resolution
9. Attributable faction estimates and case definitions for malaria in endemic areas
10. Bayesian analysis of two-component mixture distributions applied to estimating malaria attributable fractions
11. Meta-analysis of diagnostic tests with imperfect reference standards
12. The selection of ELISA cut-off points for testing antibody to Newcastle disease by two-graph receiver operating characteristic (TG-ROC) analysis
13. Latent variable modeling of diagnostic accuracy
14. Clinical validation of immunoassays: A well-designed approach to a clinical study