1,5-Hydride shift in Wolff-Kishner reduction of (20R)-3β,20, 26-trihydroxy-27-norcholest-5-en-22-one: Synthetic, quantum chemical, and NMR studies

Steroids

Volumn 67, Issue 1, 2002, Pages 31-38

  Szendi, Zsuzsanna ^a   Forgó, Péter ^a   Tasi, Gyula ^a   Böcskei, Zsolt ^b   Nyerges, Levente ^a   Sweet, Frederick ^c  

^a UNIVERSITY OF SZEGED   (Hungary)

^b EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

(20R,22S) 3 ,20,22 Trihydroxy 27 norcholest 5 ene 3, 22 diacetate; 1,5 Hydride shift; NMR; Semiempirical quantum chemical calculations; Steroids; Wolff Kishner reduction

Indexed keywords

27 NORCHOLEST 5 ENE 3BETA,20,22 TRIOL; 3BETA,20,26 TRIHYDROXY 27 NORCHOLEST 5 EN 22 ONE; ALDEHYDE; CARBENOID; CARBON; FUNCTIONAL GROUP; HYDRAZINE; HYDROGEN; KETONE DERIVATIVE; PHENYLHYDRAZINE; PHENYLHYDRAZONE DERIVATIVE; POTASSIUM HYDROXIDE; STEROID; UNCLASSIFIED DRUG;

ACIDITY; ALKALINITY; ARTICLE; CALCULATION; CHEMICAL STRUCTURE; COMPUTER MODEL; CRYSTAL STRUCTURE; DIASTEREOISOMER; HEATING; ION TRANSPORT; NUCLEAR MAGNETIC RESONANCE; PREDICTION; QUANTUM CHEMISTRY; REACTION ANALYSIS; REDUCTION; SIMULATION; STEROIDOGENESIS; STRUCTURE ANALYSIS; TEMPERATURE SENSITIVITY;

ALDEHYDES; CHOLESTANONES; CHOLESTENONES; HEAT; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL;

EID: 0036132294     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(01)00130-1     Document Type: Article

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