Osmosensitive release of neurotransmitter amino acids: Relevance and mechanisms

Neurochemical Research

Volumn 27, Issue 1-2, 2002, Pages 59-65

  Pasantes Morales, Herminia ^a   Franco, Rodrigo ^a   Ochoa, Lenin ^a   Ordaz, Benito ^a  

^a INSTITUTO DE FISIOLOGÍA CELULAR   (Mexico)

Author keywords

Hyperexcitability; Hyposmolarity; PKC; Tyrosine kinases

Indexed keywords

4 AMINOBUTYRIC ACID; ACTIN; AMINO ACID; CALCIUM ION; CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; GLUTAMIC ACID; NEUROTRANSMITTER; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; TAURINE;

AMINO ACID TRANSPORT; ARTICLE; CYTOSKELETON; ENZYME ACTIVITY; EXOCYTOSIS; MOLECULAR MECHANICS; NEUROTRANSMITTER RELEASE; NONHUMAN; OSMOLARITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

AMINO ACIDS; ANIMALS; CALCIUM; EXOCYTOSIS; HUMANS; NEUROTRANSMITTER AGENTS; SIGNAL TRANSDUCTION; WATER-ELECTROLYTE BALANCE;

EID: 0036131092     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1014850505400     Document Type: Article

References (37)

1. Volume regulation in brain cells: Cellular and molecular mechanisms
2. Hyponatremia causes large sustained reductions in brain content of multiple organic osmolytes in rats
3. Contribution of organic and inorganic osmolytes to volume regulation in rat brain cells in culture
4. Volume regulation in astrocytes: A role for taurine as osmoeffector
5. Hyposmolarity-induced taurine release in cerebellar granule cells is associated with diffusion and not with high-affinity transport
6. Efflux of osmolyte amino acids during isovolumic regulation in hippocampal slices
7. Volume regulation and the efflux of amino acids from cells in incubated slices of rat cerebral cortex. I. Characteristics of transport mechanisms
8. Volume regulation and the efflux of amino acids from cells in incubated slices of rat cerebral cortex. II. Dependence on Ca2+ ions
9. Properties and glial origin of osmotic-dependent release of taurine from the rat supraoptic nucleus
10. Does taurine act as an osmoregulatory substance in the rat brain?
11. Effects of anion channel blockers on hyposmotically induced amino acid release from the in vivo rat cerebral cortex
12. Investigation into the role of N-acetylaspartate in cerebral osmoregulation
13. Role of taurine in osmoregulation: Mechanisms and functional implications
14. Inhibition of volume regulation and efflux of osmoregulatory amino acids by blockers of Cl-transport in cultured astrocytes
15. Amino acid current through anion channels in cultured human glial cells
16. Evidence of two mechanisms for amino acid osmolyte release from hippocampal slices
17. - channel: Fresh start to the molecular identity and volume sensor
18. Pharmacological characterization of swelling-induced D-[3H]aspartate release from primary astrocyte cultures
19. Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances
20. Influence of calcium on regulatory volume decrease: Role of potassium channels
21. Intracellular signalling involved in volume regulatory decrease
22. Signalling mechanisms involved in volume regulation of intestinal epithelial cells
23. Role of calcium in astrocyte volume regulation and in the release of ions and amino acids
24. Regulatory volume decrease and associated osmolyte fluxes in cerebellar granuleneurons are calcium independent
25. Signaling events during swelling and regulatory volume decrease
26. Inhibition of volume-stimulated taurine efflux and tyrosine kinase activity in the skate red blood cell
27. Tyrosine phosphorylation modulates the osmosensitivity of volume-dependent taurine efflux from glial cells in the supraoptic nucleus
28. Influence of protein kinases on the osmosensitive release of taurine from cerebellar granule neurons
29. Hypo-osmotic cell swelling activates the p38 MAP kinase signalling cascade
30. Mitogen-activated protein and tyrosine kinases in the activation of astrocyte volume-activated chloride current
31. Activation of the osmo-sensitive chloride conductance involves P21rho and is accompanied by a transient reorganization of the F-actin cytoskeleton
32. [3H]taurine and D-[3H]aspartate release from astrocyte cultures are differently regulated by tyrosine kinases
33. Regulation of hormone secretion by acute cell volume changes: Ca(2+)-independent hormone secretion
34. Calcium-dependent and calcium-independent exocytosis
35. Stimulation of exocytosis without a calcium signal
36. Seizure and acute osmotic change: Clinical and neurophysiological aspects
37. Hyponatremia, convulsions, respiratory arrest, and permanent brain damage after elective surgeryin healthy women