Direct proton magnetic resonance determination of the pKa of the active center histidine in thiolsubtilisin

Protein Science

Volumn 11, Issue 4, 2002, Pages 965-973

  Kahyaoglu, Ara ^a   Jordan, Frank ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Catalytic triad; Protein dielectric constant; Serine protease; Thiolsubtilisin

Indexed keywords

ASPARTIC ACID; BORONIC ACID DERIVATIVE; CHYMOTRYPSIN; HISTIDINE; IMIDAZOLE DERIVATIVE; PHOSPHOSERINE; SERINE; SUBTILISIN; THIOL DERIVATIVE; THIOLACID; TRYPSIN;

ARTICLE; DIELECTRIC CONSTANT; ELECTRICITY; ENZYME DEGRADATION; IONIZATION; LABORATORY DIAGNOSIS; MEASUREMENT; PKA; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTON NUCLEAR MAGNETIC RESONANCE;

BINDING SITES; CYSTEINE; HISTIDINE; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PROTEIN CONFORMATION; SERINE ENDOPEPTIDASES; SUBTILISINS;

EID: 0036130134     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.3890102     Document Type: Article

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