Mechanical and architectural bone adaptation in early stage experimental osteoarthritis

Journal of Bone and Mineral Research

Volumn 17, Issue 4, 2002, Pages 687-694

  Boyd, Steven K ^a,b   MüLler, Ralph ^b,c   Zernicke, Ronald F ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Bone architecture; Finite element analysis; Knee; Mechanical testing; Osteoarthritis

Indexed keywords

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT; ARTICLE; BONE STRENGTH; BONE STRUCTURE; CANCELLOUS BONE; COMPRESSION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DOG; FEMUR CONDYLE; FINITE ELEMENT ANALYSIS; KNEE; NONHUMAN; OSTEOARTHRITIS; SIMULATION; YOUNG MODULUS;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BIOMECHANICS; BONE AND BONES; DISEASE MODELS, ANIMAL; DOGS; ELASTICITY; FEMUR; FINITE ELEMENT ANALYSIS; IMAGING, THREE-DIMENSIONAL; JOINTS; LIGAMENTS, ARTICULAR; OSTEOARTHRITIS; STRESS, MECHANICAL;

EID: 0036126952     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2002.17.4.687     Document Type: Article

References (37)

1. Osteoarthritis of the knee after injury to the anterior cruciate ligament or meniscus: The influence of time and age
2. The role of bone changes in the degeneration of articular cartilage in osteoarthrosis
3. Do subchondral bone changes exacerbate or precede articular cartilage destruction in osteoarthritis of the elderly?
4. The involvement of subchondral mineralized tissues in osteoarthrosis: Quantitative microscopic evidence
5. Fate of the ACL-injured patient. A prospective outcome study
6. Osteoarthritic changes in canine articular cartilage, subchondral bone, and synovium fifty-four months after transection of the anterior cruciate ligament
7. Early regional adaptation of periarticular bone mineral density after anterior cruciate ligament injury
8. A longitudinal study of subchondral plate and trabecular bone in cruciate-deficient dogs with osteoarthritis followed up for 54 months
9. Early morphometric and anisotropic change in periarticular cancellous bone in a model of experimental knee osteoarthritis quantified using microcomputed tomography
10. A new method to determine trabecular bone elastic properties and loading using micromechanical finite-element models
11. Measurement and significance of three-dimensional architecture to the mechanical integrity of trabecular bone
12. Subchondral bone in osteoarthritis
13. A decreased subchondral trabecular bone tissue elastic modulus is associated with pre-arthritic cartilage damage
14. Acute changes in trabecular bone connectivity and osteoclast activity in the ovariectomized rat in vivo
15. The relationship between three-dimensional connectivity and the elastic properties of trabecular bone
16. The canine anterior cruciate ligament transection model of osteoarthritis
17. Discoordinate gene expression of aggrecan and type II collagen in experimental osteoarthritis
18. The early molecular natural history of experimental osteoarthritis. I. Progressive discoordinate expression of aggrecan and type II procollagen messenger RNA in the articular cartilage of adult animals
19. A microtomographic system for the nondestructive evaluation of bone architecture
20. Morphometric analysis of human bone biopsies: A quantitative structural comparison of histological sections and micro-computed tomography
21. Measurement of cancellous bone strain during mechanical tests using a new extensometer device
22. The elastic properties of trabecular and cortical bone tissues are similar: Results from two microscopic measurement techniques
23. Digital image based finite element analysis for bone microstructure using conjugate gradient and Gaussian filter techniques
24. Computational strategies for iterative solutions of large FEM applications employing voxel data
25. Programming finite element computations
26. Quantification of connectivity in cancellous bone, with special emphasis on 3-D reconstructions
27. The direct examination of three-dimensional bone architecture in vitro by computed tomography
28. Changes in canine cortical and cancellous bone mechanical properties following immobilization and remobilization with exercise
29. Young's modulus, density and material properties in cancellous bone over a large density range
30. Periarticular cancellous bone changes following anterior cruciate ligament injury
31. Young's modulus of trabecular and cortical bone material: Ultrasonic and microtensile measurements
32. Elastic modulus and hardness of cortical and trabecular bone lamellae measured by nanoindentation in the human femur
33. Numerical uncertainties in finite-element modelling of trabecular bone
34. Early estrogen replacement therapy reverses the rapid loss of trabecular bone volume and prevents further deterioration of connectivity in the rat
35. Three-dimensional morphometry of the L6 vertebra in the ovariectomized rat model of osteoporosis: Biomechanical implications
36. Trabecular microstructure in the medial condyle of the proximal tibia of patients with knee osteoarthritis
37. Bone scintigraphy in the canine cruciate deficiency model of osteoarthritis. Comparison of the unstable and contralateral knee