Effect of captopril on urinary kallikrein, blood pressure and myocardial hypertrophy in diabetic spontaneously hypertensive rats

Pharmacology

Volumn 64, Issue 4, 2002, Pages 196-200

  Sharma, Jagdish N ^a,b   Kesavarao, Uma ^a  

^a SCHOOL OF PHARMACEUTICAL SCIENCES   (Malaysia)

^b KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Diabetes; Hypertension; Left ventricular hypertrophy; Spontaneously hypertensive rats; Urinary kallikrein

Indexed keywords

CAPTOPRIL; GLUCOSE; TISSUE KALLIKREIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; GLUCOSE BLOOD LEVEL; GLUCOSE URINE LEVEL; HEART LEFT VENTRICLE WALL; HEART VENTRICLE HYPERTROPHY; KALLIKREIN URINE LEVEL; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; TREATMENT OUTCOME;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD GLUCOSE; BLOOD PRESSURE; CAPTOPRIL; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE; HEART VENTRICLES; HYPERTENSION; HYPERTROPHY, LEFT VENTRICULAR; KALLIKREINS; MALE; RATS; RATS, INBRED SHR;

EID: 0036124809     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000056171     Document Type: Article

References (28)

1. Altered urinary kallikrein excretion in human hypertension
2. Important suppressive roles of the kallikrein-kinin system during the development stage of hypertension in spontaneously hypertensive rats
3. Interrelationship between the kallikrein-kinin system and hypertension
4. Relationship between kidney and urinary kininogenases
5. Blood pressure regulation by the kallikrein-kinin system
6. Abnormal regulation of renal kallikrein in experimental diabetes
7. Does kinin mediate the hypotensive action of angiotensin converting enzyme (ACE) inhibitors?
8. Suppression of hypotensive responses of captopril and enalapril by kallikrein inhibitor aprotinin in spontaneously hypertensive rats
9. Hypertensive diabetic cardio-myopathy in the rat: An experimental model of human disease
10. Changes in blood pressure, urinary kallikrein, and prostaglandin E2 in rats with streptozotocin-induced diabetes
11. Morphometric study of myocardial hypertrophy induced by abdominal aortic stenosis
12. Method for the determination of glandular kallikrein by means of chromogenic tripeptide substrate
13. Chronic hypertension induced by streptozotocin in rats
14. Renal alteration and development of hypertension in diabetic rats
15. Streptozotocin induced diabetes in the spontaneously hypertensive rats
16. Acute hypotensive effect of captopril in man modified by prostaglandin synthesis inhibition
17. Cardiac regression and blood pressure control in the Dahl rat treated with enalapril (MK421, an angiotensin converting enzyme inhibitor) and hydrochlorothiazide
18. Influence of a kinin antagonist on acute hypotension responses induced by bradykinin and captopril in spontaneously hypertensive rats
19. The genetically hypertensive rat as a model of human essential hypertension
20. Left ventricular hypertrophy and its relation to the cardiac kinin-forming system in hypertensive and diabetic rats
21. Bradykinin prevents left ventricular hypertrophy in rats
22. Abnormalities in kallikrein excretion in spontaneously hypertensive rats
23. Altered urinary kallikrein excretion in rats with hypertension
24. Oh-ishi: Suppression of rat deoxycorticosterone-salt hypertension by kallikrein-kinin system
25. Kallikrein gene therapy in hypertension, cardiovascular and renal diseases
26. Antihypertensive effect of orally administered glandular kallikrein in essential hypertension
27. Cardiac hypertrophy and antihypertensive therapy
28. Reversal of left ventricular hypertrophy in hypertensive patients: A metanalysis of 109 treated studies