Paracetamol can exacerbate irradiation-induced DNA damage [2]

British Journal of Clinical Pharmacology

Volumn 53, Issue 3, 2002, Pages 338-340

  Curnow, Alison ^a   Salter, Leo ^a   Morley, Nick ^a   Campbell, Sandra ^a   Gould, David ^a  

^a ROYAL CORNWALL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; DRUG METABOLITE; GLUTATHIONE; N ACETYL 4 BENZOQUINONIMINE; PARACETAMOL; PROSTAGLANDIN SYNTHASE; UNCLASSIFIED DRUG; XENON;

ANALGESIA; DISEASE EXACERBATION; DNA DAMAGE; DNA REPAIR; DRUG EFFECT; DRUG INACTIVATION; GEL ELECTROPHORESIS; HUMAN; IN VITRO STUDY; LETTER; LEUKOCYTE; LUNG FIBROBLAST; PAIN; PRIORITY JOURNAL; PROTEIN DEPLETION; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; ULTRAVIOLET A RADIATION;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; CELL LINE; DNA; DNA DAMAGE; FIBROBLASTS; HUMANS; LEUKOCYTES; ULTRAVIOLET RAYS;

EID: 0036124760     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0306-5251.2001.01566.x     Document Type: Letter

References (7)

1. Paracetamol-induced toxicity. Molecular and biochemical mechanisms, analogues and protective approaches
2. Paracetamol (acetaminophen) cytotoxicity in rat type II pneumocytes and alveolar macrophages in vitro
3. The cumulative effects of ultraviolet radiation on the skin: Photoageing
4. A simple technique for the quantification of low levels of DNA damage in individual cells
5. The kinetics of repair of oxidative DNA damage (strand breaks and oxidised pyrimidines) in human cells