Destiny of unspliced retroviral RNA: Ribosome and/or virion?

Journal of Virology

Volumn 76, Issue 7, 2002, Pages 3089-3094

  Butsch, Melinda ^a   Boris Lawrie, Kathleen ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DACTINOMYCIN; GAG PROTEIN; GENOMIC RNA; LEPTOMYCIN B; REV PROTEIN; VIRUS PROTEIN; VIRUS RNA;

5' UNTRANSLATED REGION; AVIAN SARCOMA VIRUS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; MURINE LEUKEMIA VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RETROVIRUS; RIBOSOME; RNA SPLICING; RNA TRANSLATION; RNA TRANSPORT; SHORT SURVEY; VIRION; VIRUS GENOME;

BIOLOGICAL TRANSPORT; PROTEIN BIOSYNTHESIS; RETROVIRIDAE; RIBOSOMES; RNA, VIRAL; VIRION; VIRUS ASSEMBLY;

EID: 0036124429     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.76.7.3089-3094.2002     Document Type: Short Survey

References (43)

1. Human immunodeficiency virus type 2 lentivirus vectors for gene transfer: Expression and potential for helper virus-free packaging
2. RNA packaging
3. An internal ribosomal entry mechanism promotes translation of murine leukemia virus gag polyprotein precursors
4. An internal ribosomal entry signal in the rat VL30 region of the Harvey murine sarcoma virus leader and its use in dicistronic retroviral vectors
5. Retroviral RNA elements integrate components of post-transcriptional gene expression
6. The human immunodeficiency virus type 1 gag gene encodes an internal ribosome entry site
7. Translation is not required to generate virion precursor RNA in human immunodeficiency virus type 1-infected T cells
8. Nuclear RNA export pathways
9. Human immunodeficiency virus type 2 lentiviral vectors: Packaging signal and splice donor in expression and encapsidation
10. Rous sarcoma virus translation revisited: Characterization of an internal ribosome entry segment in the 5′ leader of the genomic RNA
11. Comparison of viral genomic RNA sorting mechanisms in human immunodeficiency virus type 1 (HIV-1), HIV-2, and Moloney murine leukemia virus
12. Variable inhibition of cell-free translation by HIV-1 transcript leader sequences
13. Construction of a mammalian transducing vector from the genome of Moloney murine leukemia virus
14. The major human immunodeficiency virus type 2 (HIV-2) packaging signal is present on all HIV-2 RNA species: Cotranslational RNA encapsidation and limitation of Gag protein confer specificity
15. The ins and outs of HIV Rev
16. Human immunodeficiency virus types 1 and 2 differ in the predominant mechanism used for selection of genomic RNA for encapsidation
17. Deficiency of 60 to 70S RNA in murine leukemia virus particles assembled in cells treated with actinomycin D
18. Synthesis of murine leukemia virus proteins associated with virions assembled in actinomycin D-treated cells: Evidence for persistence of viral messenger RNA
19. Characterization of an internal ribosomal entry segment within the 5′ leader of avian reticuloendotheliosis virus type A RNA and development of novel MLV-REV-based retroviral vectors
20. Efficient encapsidation of human immunodeficiency virus type 1 vectors and further characterization of cis elements required for encapsidation
21. Location of cis-acting signals important for RNA encapsidation in the leader sequence of human immunodeficiency virus type 2
22. Metabolism of viral RNA in murine leukemia virus-infected cells: Evidence for differential stability of viral message and virion precursor RNA
23. The HIV-1 Rev trans-activator shuttles between the nucleus and the cytoplasm
24. The human immunodeficiency virus type 1 5′ packaging signal structure affects translation but does not function as an internal ribosome entry site structure
25. RNA is a structural element in retrovirus particles
26. An internal ribosome entry segment promotes translation of the simian immunodeficiency virus genomic RNA
27. cis elements required for high-level expression of unspliced Gag-containing message in Moloney murine leukemia virus
28. Possible role of splice acceptor site in expression of unspliced gag-containing message of Moloney murine leukemia virus
29. Rous sarcoma virus DR posttranscriptional elements use a novel RNA export pathway
30. A dual role of the putative RNA dimerization initiation site of human immunodeficiency virus type 1 in genomic RNA packaging and proviral DNA synthesis
31. Mutational analysis of the 5′ non-coding region of human immunodeficiency virus type 1: Effects of secondary structure on translation
32. Dependence of Moloney murine leukemia virus production on cell growth
33. Insertion mutagenesis to increase secondary structure within the 5′ noncoding region of a eukaryotic mRNA reduces translational efficiency
34. Identification of a human immunodeficiency virus type 2 (HIV-2) encapsidation determinant and transduction of nondividing human cells by HIV-2-based lentivirus vectors
35. Nucleic-acid-chaperone activity of retroviral nucleocapsid proteins: Significance for viral replication
36. Towards developing HIV-2 lentivirus-based retroviral vectors for gene therapy: Dual gene expression in the context of HIV-2 LTR and Tat
37. Formation of infectious progeny virus after insertion of herpes simplex thymidine kinase gene into DNA of an avian retrovirus
38. gag
39. Stabilities of avian sarcoma virus RNAs: Comparison of subgenomic and genomic species with cellular mRNAs
40. Adaptation of a retrovirus as a eucaryotic vector transmitting the herpes simplex virus thymidine kinase gene
41. Origin and general nature of retroviruses
42. Alternative translation initiation of the Moloney murine leukemia virus mRNA controlled by internal ribosome entry involving the p57/PTB splicing factor
43. Leptomycin B is an inhibitor of nuclear export: Inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA