Modulation of IgD and CD20 by ligation of CD5 on tonsillar B cells

Scandinavian Journal of Immunology

Volumn 55, Issue 1, 2002, Pages 44-52

  Morikawa, K ^a   Torii, I ^b   Morikawa, S ^c  

^a SAGAMI WOMEN'S UNIVERSITY   (Japan)

^b SHIMANE UNIVERSITY   (Japan)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD20 ANTIGEN; CD38 ANTIGEN; CD5 ANTIGEN; IMMUNOGLOBULIN D; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD5; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL CULTURE; CELL MATURATION; CELL SURFACE; CLINICAL ARTICLE; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOMODULATION; MEMORY CELL; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TONSIL CELL;

ADP-RIBOSYL CYCLASE; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD20; ANTIGENS, CD38; ANTIGENS, CD5; ANTIGENS, DIFFERENTIATION; APOPTOSIS; B-LYMPHOCYTE SUBSETS; B-LYMPHOCYTES; CELL DIFFERENTIATION; CHILD; HUMANS; IMMUNOGLOBULIN D; KINETICS; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; NAD+ NUCLEOSIDASE; PHENOTYPE; RECEPTORS, ANTIGEN, B-CELL; TONSIL;

EID: 0036124204     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.2002.00987.x     Document Type: Article

References (28)

1. + B cells
2. - B-cell chronic lymphocytic leukemia
3. Extensive and selective mutation of a rearranged VH5 gene in human B cell chronic lymphocytic leukemia
4. Molecular single-cell analysis reveals that CD5-positive peripheral blood B cells in healthy humans are characterized by rearranged Vkappa genes lacking somatic mutation
5. CD5 transgenic mice
6. The T-cell antigen CD5 acts as a receptor and substrate for the protein-tyrosine kinase p561ck
7. A role for CD5 in TCR-mediated signal transduction and thymocyte selection
8. An influence of CD5 on the selection of CD4-1ineage T cells
9. CD5 is associated with the human B cell antigen receptor complex
10. + B cell: Differential capping and modulation of IgM and CD5
11. + B cells
12. The CD5/CD72 receptor system is coexpressed with several functionally relevant counterstructures on human B cells and delivers a critical signalling activity
13. Ligation of CD5 on resting B cells, but not on resting T cells, results in apoptosis
14. Germinal center
15. Subepithelial B cells in the human palatine tonsil. I. Morphologic, cytochemical and phenotypic characterization
16. CD5-positive and CD5-negative human B cells converge to an indistinguishable population on signalling through B-cell receptors and CD40
17. - buoyant) fraction of human tonsil
18. + B cell subset with phenotypical and functional characteristics of germinal center B cells
19. CD5 is a potential selecting ligand for B cell surface immunoglobulin framework region sequences
20. Cell autonomous expression of IgD is not essential for the maturation of conventional B cells
21. The differentiation of human memory B cells into specific antibody-secreting cells is CD40 independent
22. Activation of human B cell proliferation through surface Bp35 (CD20) polypeptide or immunoglobulin receptors
23. CD20 monoclonal antibodies down-regulate IgM at the surface of B cells
24. Engagement of CD20 suppresses apoptosis in germinal center B cells
25. Long-term human B cell lines dependent on interleukin-4 and antibody to CD40
26. Memory B cell development but not germinal center formation is impaired by in vitro blockade of CD40-CD40 ligand interaction
27. Mechanism of antigen-driven selection in germinal centres
28. Hypercrosslinking surface IgM or IgD receptors on mature B cells induces apoptosis that is reversed by costimulation with IL-4 and anti-CD40