Propranolol ameliorates thrombocytopenia in patients with cirrhosis

Journal of Gastroenterology

Volumn 37, Issue 2, 2002, Pages 112-118

  Sakai, Kenji ^a   Iwao, Tadashi ^b   Oho, Kazuhiko ^a   Toyonaga, Atsushi ^a   Sata, Michio ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Iwao Hospital   (Japan)

Author keywords

Doppler flowmetry; Liver cirrhosis; Propranolol; Splenic artery; Thrombocytopenia

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; IMMUNOGLOBULIN G; PLACEBO; PROPRANOLOL; THROMBOCYTE ANTIBODY;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION FUNCTION; DOPPLER FLOWMETRY; FEMALE; HEART RATE; HEMODYNAMICS; HUMAN; HYPERSPLENISM; HYPOTHESIS; LIVER CIRRHOSIS; MALE; PRIORITY JOURNAL; PULSE WAVE; RANDOMIZED CONTROLLED TRIAL; SPLEEN ARTERY; THROMBOCYTE COUNT; THROMBOCYTOPENIA; VASOCONSTRICTION;

ADRENERGIC BETA-ANTAGONISTS; FEMALE; HUMANS; HYPERTENSION, PORTAL; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PLATELET COUNT; PROPRANOLOL; SPLENIC ARTERY; THROMBOCYTOPENIA; VASODILATOR AGENTS;

EID: 0036122299     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/s005350200005     Document Type: Article

References (40)

1. Pooling of platelets in the spleen: Role in the pathogenesis of "hypersplenic" thrombocytopenia
2. Increased splenic pooling and the pathogenesis of hypersplenism
3. The relationship between splenic platelet pool and spleen size
4. The hypersplenic spleen: A contractile reservoir of granulocytes and platelets
5. Measurement of spleen size and its relation to hypersplenism and portal hemodynamics in portal hypertension due to hepatic cirrhosis
6. Study of platelet-associated immunoglobulins of IgG, IgM, IgA, and IgE classes and platelet kinetics in 33 patients with idiopathic thrombocytopenic purpura
7. Interrelationships between platelet count, platelet IgG, serum IgG, immune complexes and severity of liver disease
8. Mechanism of thrombocytopenia in liver cirrhosis: Kinetics of indium-111 tropolone labelled platelets
9. Splenectomy for massive splenomegaly
10. Elective splenectomy: An analysis of 220 operations
11. The effect of portocaval shunt on hypersplenism
12. Effect of portosystemic shunt on hypersplenism: Clinical study in 129 patients with cirrhosis
13. Correction of hypersplenism following distal splenorenal shunt
14. The effect of the distal splenorenal shunt on hypersplenism
15. Reversal of hypersplenism following orthotopic liver transplantation
16. Does auxiliary heterotopic liver transplantation reverse hypersplenism and portal hypertension?
17. Partial splenic embolization. An effective alternative to splenectomy for hypersplenism
18. Partial splenic embolization for the treatment of hypersplenism in cirrhosis
19. Changes in platelet kinetics after a partial splenic arterial embolization in cirrhotic patients with hypersplenism
20. Improvement of thrombocytopenia due to hypersplenism after transjugular intrahepatic portosystemic shunt placement in cirrhotic patients
21. Beta-adrenergic blockade and gastrointestinal system
22. Comparison of the effects of a cardioselective and a nonselective β-blocker on portal hypertension in patients with cirrhosis
23. Selective and non-selective beta receptor blockade in the reduction of portal pressure in patients with cirrhosis and portal hypertension
24. The effect of selective blockade of β 2-adrenergic receptors on portal and systemic hemodynamics in portal hypertensive rat model
25. Noninvasive hemodynamic measurements of superior mesenteric artery in the prediction of portal pressure response to propranolol
26. Effects of long-acting propranolol and verapamil on blood pressure, platelet function, metabolic and rheological properties in hypertension
27. Transection of the oesophagus for bleeding oesophageal varices
28. Determination of cardiac output in critically ill patients by dual beam Doppler echocardiography
29. Clinical application of an ultrasonic duplex system in the quantitative measurement of portal blood flow
30. Postprandial splanchnic hemodynamic response in patients with cirrhosis of the liver: Evaluation with "triple-vessel" duplex US
31. Studies of human platelet-α-granule release in vivo
32. Measurement of thromboxane B2 in human plasma or serum by radioimmunoassay
33. A sensitive radioimmunoassay for 6-keto-prostaglandin F1 α: Preliminary observation on circulating concentrations
34. Quantification of platelet-associated IgG with competitive solid-phase enzeyme immunoassay
35. Fetal blood velocity waveform
36. Control of the splanchnic circulation in man. Role of β-adrenergic receptors
37. Splenic Doppler impedance indices: Influence of different portal hemodynamic conditions
38. Is inadequate thrombopoietin production a major cause of thrombocytopenia in cirrhosis of the liver?
39. Thrombopoietin levels in patients with cirrhosis before and after orthotopic orthotopic liver transplantation
40. Enhancement of portal pressure reduction by the association of isosorbide-5-mononitrate to propranolol administration in patients with cirrhosis