Glycine-extended gastrin-17 stimulates acid secretion only via CCK-2 receptor-induced histamine release in the totally isolated vascularly perfused rat stomach

Acta Physiologica Scandinavica

Volumn 174, Issue 2, 2002, Pages 125-130

  Cui, G L ^a   Sandvik, A K ^a   Munkvold, B ^a   Waldum, H L ^a,b  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^b TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

Author keywords

Cholecystokinin 2 receptor; Enterochromaffin like cell; Gastric acid secretion; Glycine extended gastrin 17; Histamine; Isolated rat stomach

Indexed keywords

CHOLECYSTOKININ RECEPTOR; GASTRIN 17; GASTRIN DERIVATIVE; GLYCINE DERIVATIVE; HISTAMINE; HISTAMINE H2 RECEPTOR; RANITIDINE; RECEPTOR SUBTYPE;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; HISTAMINE RELEASE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH; STOMACH ACID; STOMACH ACID SECRETION; STOMACH BLOOD FLOW;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; ENTEROCHROMAFFIN CELLS; GASTRIC ACID; GASTRINS; HISTAMINE; MALE; PERFUSION; RANITIDINE; RATS; RATS, WISTAR; RECEPTORS, CHOLECYSTOKININ; STOMACH;

EID: 0036121823     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.2002.00933.x     Document Type: Article

References (27)

1. Regulation of parietal cell calcium signaling in gastric glands
2. Role of gastrin/CCK-B receptors in meal-stimulated acid secretion in rats
3. The CCK-2 receptor is located on the ECL cell, but not on the parietal cell
4. Trophic effect of gastrin on the enterochromaffin like cells of the rat stomach: Establishment of a dose-response relationship
5. Gastrin-evoked secretion of pancreastatin and histamine from ECL cells and of acid from parietal cells in isolated, vascularly perfused rat stomach. Effects of isobutyl methylxantin and α-fluoromethylhistidine
6. Time course of hypertrophic and ultrastructral responses of rat stomach enterochromaffin-like cells to sustained hypergastrinemia
7. Glycine-extended gastrin synergizes with gastrin-17 to stimulate acid secretion in gastrin-deficient mice
8. Inhibition of the α-amidation of gastrin: Effect on gastric acid secretion
9. Gastrin and the trophic control of gastric mucosa
10. Glycine-extended gastrin potentiates gastrin stimulated gastric acid secretion in rats
11. Pentagastrin-stimulated histamine release and acid secretion from the totally isolated vascularly perfused rat stomach
12. +-ATPase α-subunit gene expression through a novel receptor
13. The preparation of bioactive 125 I-gastrin, using iodo-gen as oxidizing agent, and the use of this tracer in receptor studies
14. The effect of pentagastrin on the gastric secretion by the totally isolated vascularly perfused rat stomach
15. Effect of pentagastrin on gastric acid secretion in the totally isolated vascularly perfused rat stomach stimulated with the phosphodiesterase inhibitor isobutyl methylxantine
16. Gastric acid secretion in the totally isolated, vascularly perfused rat stomach. A selective muscarinic-1 agent does, whereas gastrin does not, augment maximal histamine-stimulated acid secretion
17. Characterization of glycine extended gastrin (G-GLY) biological effects on canine gastric ECL cells
18. CCK-B (gastrin) receptor regulates gastric histamine release and acid secretion
19. Rat gastric histamine release: A sensitive gastrin bioassay
20. Biological activity of carboxy-terminal gastrin analogues
21. Growth-promoting effects of glycine-extended progastrin
22. Role of gastrin/CCK-B receptor in the regulation of gastric acid secretion in rat
23. Gastrin-histamine sequence in the regulation of gastric acid secretion
24. Trophic effect of histamine on the stomach
25. Radioimmunoassay of histamine
26. Gastrointestinal hormones
27. Autonomic regulation of somatostatin release: Studies with primary cultures of canine fundic mucosal cells