Interaction between parvovirus NS2 protein and nuclear export factor Crml is important for viral egress from the nucleus of murine cells

Journal of Virology

Volumn 76, Issue 7, 2002, Pages 3257-3266

  Miller, Cathy L ^a   Pintel, David J ^a  

^a University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR FACTOR; SINGLE STRANDED DNA;

ANIMAL CELL; ARTICLE; DNA BINDING; DNA REPLICATION; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PARVOVIRUS; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROGENY; VIRUS CAPSID; VIRUS CELL INTERACTION; VIRUS INFECTION; VIRUS MUTATION; VIRUS REPLICATION;

ANIMALS; CAPSID; CELL LINE; CELL NUCLEUS; DNA, VIRAL; HUMANS; KARYOPHERINS; MICE; MINUTE VIRUS OF MICE; PROTEIN BINDING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 0036121109     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.76.7.3257-3266.2002     Document Type: Article

References (24)

1. RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase
2. Nuclear export factor CRM1 interacts with nonstructural proteins NS2 from parvovirus minute virus of mice
3. Nonstructural proteins NS2 of minute virus of mice associate in vivo with 14-3-3 protein family members
4. Cloning of MVM cDNAs and preliminary analysis of individual viral proteins expressed in murine cells
5. The NS2 polypeptide of parvovirus MVM is required for capsid assembly in murine cells
6. The autonomous parvovirus encodes two nonstructural proteins in addition to its capsid polypeptides
7. Alternate splicing in a parvoviral nonstructural gene links a common amino-terminal sequence to downstream domains which confer radically different localization and turnover characteristics
8. DNA replication in the autonomous parvoviruses
9. CRM1 is an export receptor for leucine-rich nuclear export signals
10. Intron definition is required for excision of the minute virus of mice small intron and definition of the upstream exon
11. The N-terminal nuclear export sequence of IκBα is required for RanGTP-dependent binding to CRM1
12. A beta-stranded motif drives capsid protein oligomers of the parvovirus minute virus of mice into the nucleus for viral assembly
13. Phosphorylation status of the parvovirus minute virus of mice particle: Mapping and biological relevance of the major phosphorylation sites
14. Two-way trafficking with Ran
15. Construction of an infectious molecular clone of the autonomous parvovirus minute virus of mice
16. The NS2 protein generated by the parvovirus minute virus of mice is degraded by the proteasome in a manner independent of ubiquitin chain elongation or activation
17. 2-3-containing DNA
18. The small nonstructural protein (NS2) of MVM is required for efficient DNA replication and infectious virus production in a cell-type-specific manner
19. Sequence motifs in the replicator protein of parvovirus MVM essential for nicking and covalent attachment to the viral origin: Identification of the linking tyrosine
20. Nuclear targeting of the parvoviral replicator molecule NS1: Evidence for self-association prior to nuclear transport
21. CRM1 mediates nuclear export of nonstructural protein 2 from parvovirus minute virus of mice
22. Reciprocal productive and restrictive virus-cell interactions of immunosuppressive and prototype strains of minute virus of mice
23. The minor capsid protein VP1 of the autonomous parvovirus MVM is not required for encapsidation of progeny single-strand DNA but is required for infectivity
24. Nuclear export receptors: From importin to exportin