Validation of a capillary gas chromatographic method for the determination of Sildenafil Citrate in its pharmaceutical formulations (Viagra). Experimental design for evaluating the ruggedness of the method

Chromatographia

Volumn 55, Issue 9-10, 2002, Pages 601-606

  Berzas, J J ^a   Rodriguez J ^a   Villasenor M J ^a   Contento, A M ^a   Cabello, M P ^a  

^a UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

Author keywords

Gas chromatography; Pharmaceutical sample analysis; Sildenafil Citrate; Validation and ruggedness

Indexed keywords

DRUG METABOLITE; EXCIPIENT; SILDENAFIL; UK 103320; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CAPILLARY GAS CHROMATOGRAPHY; DRUG FORMULATION; DRUG STABILITY; EXPERIMENTAL DESIGN; FACTORIAL ANALYSIS; LINEAR SYSTEM; MASS SPECTROMETRY; PRESSURE; PRIORITY JOURNAL; REPRODUCIBILITY; SAMPLE SIZE; SENSITIVITY AND SPECIFICITY; STANDARD; TEMPERATURE; TIME; VALIDATION PROCESS;

EID: 0036115193     PISSN: 00095893     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02492908     Document Type: Article

References (25)

1. Analytical method validation: Bioavailability. Bioequivalence and pharmacokinetic studies. Conference report