Trafficking of the Salmonella vacuole in macrophages

Traffic

Volumn 3, Issue 3, 2002, Pages 161-169

  Holden, David W ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Endocytic pathway; Macrophage; Salmonella; Trafficking; Virulence

Indexed keywords

BACTERIAL GENE; BACTERIAL VIRULENCE; CELL DIVISION; CELL MEMBRANE; CELL SURVIVAL; CELL VACUOLE; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; GENE FUNCTION; GENE IDENTIFICATION; INTRACELLULAR TRANSPORT; LYSOSOME; MACROPHAGE; NONHUMAN; OPERON; PATHOGENICITY; PLASMID; PRIORITY JOURNAL; REVIEW; SALMONELLA ENTERICA;

ANIMALS; BACTERIAL PROTEINS; CYTOSKELETON; ENDOCYTOSIS; GLYCOPROTEINS; MACROPHAGES; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; SALMONELLA ENTERICA; VACUOLES;

EID: 0036112327     PISSN: 13989219     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0854.2002.030301.x     Document Type: Review

References (88)

1. Differential bacterial survival, replication, and apoptosis-inducing ability of Salmonella serovars within human and murine macrophages
2. Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent
3. Murine salmonellosis studied by confocal microscopy. Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phagocytes in vivo
4. Use of confocal microscopy to detect Salmonella typhimurium within host cells associated with Spv-mediated intracellular proliferation
5. Intracellular replication of Salmonella typhimurium strains in specific subsets of splenic macrophages in vivo
6. The Mycobacterium tuberculosis phagosome interacts with early endosomes and is accessible to exogenously administered transferrin
7. Mycobacterium-containing phagosomes are accessible to early endosomes and reflect a transitional state in normal phagosome biogenesis
8. The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes
9. Evidence that Dot-dependent and -independent factors isolate the Legionella pneumophila phagosome from the endocytic network in mouse macrophages
10. Intracellular trafficking of Brucella abortus in J774 macrophages
11. Dynamics of growth and death within a Salmonella typhimurium population during infection of macrophages
12. Inhibition of macrophage phagosome-lysosome fusion by Salmonella typhimurium
13. The unique trafficking pattern of Salmonella typhimurium-containing phagosomes in murine macrophages is independent of the mechanism of bacterial entry
14. Biogenesis of Salmonella typhimurium-containing vacuoles in epithelial cells involves interactions with the early endocytic pathways
15. Expression of constitutively active Rab5 uncouples maturation of the Salmonella-containing vacuole from intracellular replication
16. Live Salmonella modulate expression of Rab proteins to persist in a specialized compartment and escape transport to lysosomes
17. Live Salmonella recruits N-ethylmaleimide-sensitive fusion protein on phagosomal membrane and promotes fusion with early endosome
18. Rapid and complete fusion of macrophage lysosomes with phagosomes containing Salmonella typhimurium
19. Phagolysosome formation, cyclic adenosine 3′.5′-monophosphate and the fate of Salmonella typhimurium within mouse peritoneal macrophages
20. Specific inhibition of phagosome-lysosome fusion in murine macrophages mediated by Salmonella typhimurium infection
21. A Salmonella virulence protein that inhibits cellular trafficking
22. A role for the PhoP/Q regulon in inhibition of fusion between lysosomes and Salmonella-containing vacuoles in macrophages
23. Salmonella maintains the integrity of its intracellular vacuole through the action of SifA
24. The rab7 GTPase controls the maturation of Salmonella typhimurium-containing vacuoles in HeLa cells
25. Targeting of Salmonella typhimurium to vesicles containing lysosomal membrane glycoproteins bypasses compartments with mannose 6-phosphate receptors
26. Salmonella induces the formation of filamentous structures containing lysosomal membrane glycoproteins in epithelial cells
27. Salmonella typhimurium loci involved in survival within macrophages
28. Salmonella typhimurium virulence genes are induced upon bacterial invasion into phagocytic and nonphagocytic cells
29. Induction of Salmonella stress proteins upon infection of macrophages
30. Fluorescence-based isolation of bacterial genes expressed within host cells
31. Identification of a virulence locus encoding a second type III secretion system in Salmonella typhimurium
32. Identification of a pathogenicity island required for Salmonella survival in host cells
33. Functional analysis of ssaJ and the ssaK/U operon, 13 genes encoding components of the type III secretion apparatus of Salmonella Pathogenicity Island 2
34. Supramolecular structure of the Salmonella typhimurium type III protein secretion system
35. Assembly and function of type III secretory systems
36. Simultaneous identification of bacterial virulence genes by negative selection
37. Genes encoding putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2 are required for bacterial virulence and proliferation in macrophages
38. Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival
39. OmpR regulates the two-component system ssrA-ssrB in Salmonella pathogenicity island 2
40. Environmental regulation of Salmonella pathogenicity island 2 gene expression
41. pH-dependent secretion of SseB, a product of the SPI-2 type III secretion system of Salmonella typhimurium
42. SseBCD proteins are secreted by the type III secretion system of Salmonella pathogenicity island 2 and function as a translocon
43. Acidification of phagosomes containing Salmonella typhimurium in murine macrophages
44. Translocation of a hybrid YopE-adenylate cyclase from Yersinia enterocolitica into HeLa cells
45. A conserved amino acid sequence directing intracellular type III secretion by Salmonella typhimurium
46. Aggregation of host endosomes by Salmonella requires SPI2 translocation of SseFG and involves SpvR and the fms-aroE intragenic region
47. Remodelling of the actin cytoskeleton is essential for replication of intravacuolar Salmonella
48. Identification of a Salmonella virulence gene required for formation of filamentous structures containing lysosomal membrane glycoproteins within epithelial cells
49. SifA permits survival and replication of Salmonella typhimurium in murine macrophages
50. Influence of the Salmonella typhimurium pathogenicity island 2 type III secretion system on bacterial growth in the mouse
51. Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase
52. Salmonella pathogenicity island 2-encoded type III secretion system mediates exclusion of NADPH oxidase assembly from the phagosomal membrane
53. Defective localization of the NADPH phagocyte oxidase to Salmonella-containing phagosomes in tumor necrosis factor p55 receptor-deficient macrophages
54. S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells
55. Identification of SopE2 from Salmonella typhimurium, a conserved guanine nucleotide exchange factor for Cdc42 of the host cell
56. SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase
57. A Salmonella inositol polyphosphatase acts in conjunction with other bacterial effectors to promote host cell actin cytoskeleton rearrangements and bacterial internalization
58. A Salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion
59. The Salmonella spvB virulence gene encodes an enzyme that ADP-ribosylates actin and destabilizes the cytoskeleton of eukaryotic cells
60. Actin is ADP-ribosylated by the Salmonella enterica virulence-associated protein SpvB
61. The Salmonella typhimurium virulence plasmid increases the growth rate of salmonellae in mice
62. Salmonella typhimurium activates virulence gene transcription within acidified macrophage phagosomes
63. Bacterial genetics by flow cytometry: Rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction
64. 2+ as an extracellular signal: Environmental regulation of Salmonella virulence
65. The pleiotropic two-component regulatory system PhoP-PhoQ
66. A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence
67. Identification of PhoP-PhoQ activated genes within a duplicated region of the Salmonella typhimurium chromosome
68. The phoP locus influences processing and presentation of Salmonella typhimurium antigens by activated macrophages
69. Salmonella spp. are cytotoxic for cultured macrophages
70. Salmonella exploits caspase-1 to colonize Peyer's patches in a murine typhoid model
71. Salmonella enterica serovars Typhimurium and Dublin can lyse macrophages by a mechanism distinct from apoptosis
72. Salmonella induces macrophage death by caspase-1-dependent necrosis
73. Salmonella pathogenicity island 1-independent induction of apoptosis in infected macrophages by Salmonella enterica serotype Typhimurium
74. The phagosome proteome: Insight into phagosome functions
75. Brucella suis-impaired specific recognition of phagosomes by lysosomes due to phagosomal membrane modifications
76. Involvement of ezrin/moesin in de novo actin assembly on phagosomal membranes
77. Salmonella pathogenicity island 2-encoded proteins SseC and SseD are essential for virulence and are substrates of the type III secretion system
78. Regulation of virulence genes by environmental signals in Salmonella typhimurium
79. Salmonella SsrB activates a global regulon of horizontally acquired genes
80. The Salmonella selC locus contains a pathogenicity island mediating intramacrophage survival
81. Role of Salmonella typhimurium Mn-superoxide dismutase (SodA) in protection against early killing by J774 macrophages
82. Novel Salmonella enterica serovar Typhimurium protein that is indispensable for virulence and intracellular replication
83. SlyA, a transcriptional regulator of Salmonella typhimurium, is required for resistance to oxidative stress and is expressed in the intracellular environment of macrophages
84. The alternative sigma factor, sigmaE, is critically important for the virulence of Salmonella typhimurium
85. Characterization of the Salmonella typhimurium pagC/pagD chromosomal region
86. Type III protein secretion systems in bacterial pathogens of animals and plants
87. Supermolecular structure of the enteropathogenic Escherichia coli type III secretion system and its direct interaction with the EspA-sheath-like structure
88. A novel EspA-associated surface organelle of enteropathogenic Escherichia coli involved in protein translocation into epithelial cells