Medical treatment of patients with infantile spasms

Clinical Neuropharmacology

Volumn 25, Issue 2, 2002, Pages 61-70

  Mikati, Mohamad A ^a   Lepejian, Garine A ^a   Holmes, Gregory L ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

Author keywords

Adrenocorticotropic hormone; Antiepileptic drugs; Infantile spasm; Steroids; West syndrome

Indexed keywords

CORTICOSTEROID; CORTICOTROPIN; IMMUNOGLOBULIN; LAMOTRIGINE; NITRAZEPAM; PLACEBO; PREDNISONE; PROTIRELIN; PYRIDOXINE; TOPIRAMATE; VALPROIC ACID; VIGABATRIN; ZONISAMIDE;

CUSHINGOID SYNDROME; DISEASE ASSOCIATION; DROWSINESS; DRUG EFFICACY; ENDOCRINE DISEASE; GASTROINTESTINAL SYMPTOM; HUMAN; HYPERTENSION; HYPERTROPHIC CARDIOMYOPATHY; IMMUNE DEFICIENCY; INFANT; INFANTILE SPASM; KETOGENIC DIET; MAJOR CLINICAL STUDY; MUSCLE HYPOTONIA; NAUSEA AND VOMITING; PRIORITY JOURNAL; PROGNOSIS; RESPIRATION DEPRESSION; RETINOPATHY; REVIEW; SEIZURE; TUBEROUS SCLEROSIS; UNITED STATES; WEST SYNDROME;

EID: 0036110470     PISSN: 03625664     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002826-200203000-00001     Document Type: Review

References (98)

1. On a peculiar form of infantile convulsions
2. The classification of childhood seizures and epilepsy syndromes
3. Infantile spasms
4. Infantile spasms
5. Epilepsy
6. Precise characterization and quantification of infantile spasms
7. Infantile spasms
8. Infantile spasms
9. Twenty-four-hour ambulatory EEG monitoring in infantile spasms
10. Visual inattention in West syndrome: A neurologic and neurofunctional imaging study
11. Infantile spasms
12. Hypsarrhythmia: Variations on the theme
13. Correlation ofhypsarrhythmic patterns with etiology and outcome
14. Hypsarrhythmia, frequency of variant pattern and correlation with etiology and outcome
15. Report of the task force on pertussis and pertussis immunization 1988
16. The ricochet of magic bullets: Summary of the Institute of Medicine report, "Adverse effects of pertussis and rubella vaccines"
17. The epidemiology and natural history of infantile spasms
18. A prospective study of infantile spasms: Clinical and therapeutic correlations
19. Infantile spasms: Outcome and prognostic factors of cryptogenic and symptomatic groups
20. Long-term prognosis of 150 cases of "West syndrome"
21. Long-term prognosis after infantile spasms: A statistical study of prognostic factors in 200 cases
22. Mental outcome in West syndrome: Prognostic value of some clinical factors
23. Ipsiversive ictal eye movements in a child with cerebral dysgenesis
24. Facilitation of infantile spasms by partial seizures
25. Focal features in West syndrome indicating candidacy for surgery
26. Pathophysiology of massive infantile spasms: Perspective on the putative role of the brain adrenal axis
27. Organization of CRF immunoreactive cells and fibers in the rat brain: Immunohistochemical studies
28. Changes in the Timm sulfide silver staining pattern of the rat hippocampus and fascia dentata following early postnatal deafferentation
29. ACTH prednisone in childhood seizure disorders
30. A propos de 21 cas d'hypsarhythmie de Gibbs. Son traitement spectaculaire par I'ACTH
31. Double-blind study of ACTH versus prednisone therapy in infantile spasms
32. A simple, effective, and well-tolerated treatment regime for West syndrome
33. Treatment of infantile spasms with high-dose ACTH: Efficacy and plasma levels of ACTH and cortisol
34. Prospective study of outcome of infants with infantile spasms treated during controlled studies of ACTH and prednisone
35. The effects of ACTH therapy upon infantile spasm
36. Clinical and laboratory observations. The efficacy of corticotropin in primary infantile spasms
37. ACTH therapy in infantile spasms: Relationship between dose of ACTH and initial effect on long-term prognosis
38. Long-term prognosis of patients with infantile spasms following ACTH therapy
39. Seizures and steroids
40. Infantile spasms. Favorable response to steroid therapy
41. Medical treatment
42. Treatment of infantile spasms
43. Pneumocystis carinii pneumonia associated with adrenocorticotrophic hormone treatment for infantile spasms
44. Cardiac hypertrophy associated with ACTH therapy for childhood seizure disorder
45. Hypertrophic cardiomyopathy during corticotropin therapy for infantile spasms. A clinical and echocardiographic study
46. Cardiac size and function during ACTH hormone-induced systolic systemic hypertension in infants
47. Changes of thyroid hormone levels during ACTH therapy in epileptic children
48. The effect of non-depot ACTH (1-24) on infantile spasms
49. West syndrome: Individualized ACTH therapy
50. Treatment of infantile spasms
51. Advances in therapy of infantile spasms. Current knowledge of actions of ACTH and corticosteroids
52. Therapeutic trial of vigabatrin in refractory infantile spasms
53. Vigabatrin in the treatment of childhood epilepsies: A single-blind placebo-controlled study
54. Vigabatrin in infantile spasms
55. Early treatment of infantile spasms with vigabatrin monotherapy: Results in 4 patients
56. Vigabatrin in infantile spasm - Why add on?
57. Vigabatrin in the treatment of infantile spasms
58. Vigabatrin as initial therapy for infantile spasms: A European retrospective survey
59. Randomized trial comparing vigabatrin and hydrocortisone in infantile spasms due to tuberous sclerosis
60. Vigabatrin versus ACTH as first-line treatment for infantile spasms: A randomized, prospective study
61. ACTH versus vigabatrin therapy in infantile spasms: A retrospective study
62. Randomised, placebo-controlled study of vigabatrin as first line treatment of infantile spasms
63. Visual field constriction is not limited to children treated with vigabatrin
64. Therapy of infantile spasms with valproate: Results of a prospective study
65. Use of valproic acid in treatment of infantile spasms
66. Short term effects of valproate on infantile spasms
67. Treatment of infantile spasms with sodium dipropylacetic acid
68. Valproate toxicity
69. Ammonia and carnitine concentrations in children treated with sodium valproate compared with other anticonvulsant drugs
70. Fatal liver failure in 16 children with valproate therapy
71. Valproic acid hepatic fatalities: A retrospective review
72. Treatment of infantile spasms and Lennox-Gastaut syndrome with clonazepam (Rivotril)
73. Antiepileptic effect and serum levels of chlorazepate on children with refractory seizures
74. Benzodiazepines in the treatment of children with epilepsy
75. Infantile spasms. Comparative trial of nitrazepam and corticotropin
76. Pyridoxine dependent epilepsy EEG spectrum, and long term follow up
77. Treatment of the West syndrome with high-dose pyridoxal phosphate
78. High dose B6 treatment in infantile spasms
79. Treatment of infantile spasms with high dosage vitamin B6
80. Combination therapy of infantile spasms with high-dose pyridoxal phosphate and low-dose corticotropin
81. Outcome of initial treatment with high-dose vitamin B6, valproate sodium or clonazepam in West syndrome
82. Alternative epilepsy therapies: The ketogenic diet, immunoglobulins, and steroids
83. High-dose intravenous immunoglobulin treatment in cryptogenic West syndrome and Lennox-Gastaut syndrome: An add-on study
84. Influence of ACTH on serum hormone content and its anticonvulsant action towards infantile spasms
85. A pilot study on the anticonvulsive effects of a thyrotropin-releasing hormone analog in intractable epilepsy
86. Clinical effects of thyrotropin-releasing hormone for severe epilepsy in childhood: A comparative study with ACTH therapy
87. Efficacy of felbamate in partial epilepsy in children
88. Felbamate for refractory infantile spasms
89. Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome)
90. The use of felbamate to treat infantile spasms
91. Lamotrigine in absence and primary generalized epilepsies
92. Lamotrigine in infantile spasms
93. Efficacy, tolerability, and kinetics of lamotrigine in infants
94. A pilot study of topiramate in the treatment of infantile spasms
95. Treatment of infantile spasms with zonisamide
96. Surgery for intractable infantile spasms: Neuroimaging perspectives