The FORKO mouse as a genetic model for exploring estrogen replacement therapy

Journal of Reproductive Medicine for the Obstetrician and Gynecologist

Volumn 47, Issue 5, 2002, Pages 412-418

  Sairam, M Ram ^a   Danilovich, Natalia ^a   Lussier Cacan, Suzanne ^a  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

Estrogen replacement therapy; Menopause; Mice, knockout

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR; FOLLITROPIN RECEPTOR; TAMOXIFEN; ANTIESTROGEN; APOLIPOPROTEIN E; CHOLESTEROL; ESTRADIOL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TESTOSTERONE; TRIACYLGLYCEROL;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY FAT; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ESTROGEN ACTIVITY; ESTROGEN DEFICIENCY; ESTROGEN THERAPY; EVALUATION; FEMALE; GENETIC MODEL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; LIPID BLOOD LEVEL; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TISSUE REACTION; TREATMENT OUTCOME; ADIPOSE TISSUE; ANIMAL; BIOLOGICAL MODEL; BLOOD; DISEASE MODEL; GENETICS; MOUSE MUTANT; UTERUS; VAGINA;

ADIPOSE TISSUE; ANIMAL; APOLIPOPROTEINS E; CHOLESTEROL; DISEASE MODELS, ANIMAL; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGEN REPLACEMENT THERAPY; FEMALE; LIPOPROTEINS, HDL CHOLESTEROL; MICE; MICE, KNOCKOUT; MODELS, GENETIC; RECEPTORS, FSH; SUPPORT, NON-U.S. GOV'T; TAMOXIFEN; TESTOSTERONE; TRIGLYCERIDES; UTERUS; VAGINA; ANIMALS; CHOLESTEROL, HDL;

EID: 0036105485     PISSN: 00247758     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Menopause: The aging of multiple pacemakers
2. Tissue-specific estrogens: The promise for the future
3. Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women
4. Estrogen receptor null mice: What have we learned and where will they lead us?
5. The ovariectomized rat model of postmenopausal bone loss
6. Ovarian adrenergic nerves play a role in maintaining preovulatory steroid secretion
7. Impairing folliclestimulating hormone (FSH) signaling in vivo: Targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance
8. Estrogen deficiency, obesity and skeletal abnormalities in follicle-stimulating hormone receptor knockout (FORKO) female mouse
9. The FORKO mouse as a genetic model for hormone replacement therapy
10. Lactotransferrin is the major estrogen inducible protein of mouse uterine secretions
11. Plasma concentration of apolipoprotein E in intermediate-sized remnant-like lipoproteins in normolipidemic and hyperlipidemic subjects
12. Body weight, body fat distribution and hormonal replacement therapy in early postmenopausal women
13. Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells
14. Overexpression of apolipoprotein E in transgenic mice: Marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia
15. Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 study
16. Is abdominal body fat distribution a major explanation for the sex difference in the incidence of myocardial infarction?: The study of men born in 1913 and the study of women in Goteborg, Sweden
17. The HERS trial results: Paradigms lost?: Heart and Estrogen/Progestin Replacement Study
18. Estrogen, selective estrogen receptor modulation and coronary heart disease: Something or nothing