Epitope mapping of a monoclonal antibody against human thrombin by H/D-exchange mass spectrometry reveals selection of a diverse sequence in a highly conserved protein

Protein Science

Volumn 11, Issue 6, 2002, Pages 1300-1308

  Baerga Ortiz, Abel ^a   Hughes, Carrie A ^a   Mandell, Jeffrey G ^a   Komives, Elizabeth A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

BIACORE; Epitope mapping; Hydrogen deuterium exchange; MALDI; Thrombin

Indexed keywords

EPITOPE; MONOCLONAL ANTIBODY; PROTEIN G; THROMBIN; THROMBOMODULIN; DEUTERIUM; HYDROGEN; PROTEIN C;

ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; ARTICLE; BINDING SITE; COVALENT BOND; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; ANIMAL; EPITOPE MAPPING; GENETICS; HUMAN; IMMUNOLOGY; INSTRUMENTATION; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; MOUSE; PROTEIN BINDING;

BOVINAE; MURINAE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; DEUTERIUM; EPITOPE MAPPING; HUMANS; HYDROGEN; MICE; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN C; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; THROMBIN;

EID: 0036102156     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.4670102     Document Type: Article

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