Envelope-dependent, cyclophilin-independent effects of glycosaminoglycans on human immunodeficiency virus type 1 attachment and infection

Journal of Virology

Volumn 76, Issue 12, 2002, Pages 6332-6343

  Zhang, Yi jun ^a   Hatziioannou, Theodora ^a   Zang, Trinity ^a   Braaten, Douglas ^a   Luban, Jeremy ^a   Goff, Stephen P ^a   Bieniasz, Paul D ^a  

^a AARON DIAMOND AIDS RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHILIN A; GLYCOPROTEIN GP 120; GLYCOSAMINOGLYCAN;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL LINE; CELL SURFACE; CHO CELL; CONTROLLED STUDY; GENE SEQUENCE; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TARGET CELL; VIRION; VIRUS ADSORPTION; VIRUS ENVELOPE;

ANIMALS; CHO CELLS; CRICETINAE; CYCLOPHILINS; GENE PRODUCTS, ENV; GENE PRODUCTS, GAG; GLYCOSAMINOGLYCANS; HIV ENVELOPE PROTEIN GP120; HIV INFECTIONS; HIV-1; HUMANS; JURKAT CELLS; PEPTIDE FRAGMENTS; VIRION;

EID: 0036100084     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.76.12.6332-6343.2002     Document Type: Article

References (42)

1. Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus
2. Multiple blocks to human immunodeficiency virus type 1 replication in rodent cells
3. Cyclosporine A-resistant human immunodeficiency virus type 1 mutants demonstrate that Gag encodes the functional target of cyclophilin A
4. Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription
5. Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cells
6. Dextran sulfate blocks antibody binding to the principal neutralizing domain of human immunodeficiency virus type 1 without interfering with gp 120-CD4 interactions
7. The fusion domain of HIV gp41 interacts specifically with heparan sulfate on the T-lymphocyte cell surface
8. Soluble CD4 induces the binding of human immunodeficiency virus type 1 to cells via the V3 loop of glycoprotein 120 and specific sites in glycoprotein 41
9. Binding of recombinant feline immunodeficiency virus surface glycoprotein to feline cells: Role of CXCR4, cell-surface heparans, and an unidentified non-CXCR4 receptor
10. Tumor formation dependent on proteoglycan biosynthesis
11. Animal cell mutants defective in glycosaminoglycan biosynthesis
12. Specific incorporation of cyclophilin A into HIV-1 virions
13. Enhancement of human immunodeficiency virus type 1 infection by the CC-chemokine RANTES is independent of the mechanism of virus-cell fusion
14. Inhibition of plating of human T cell leukemia virus type 1 and syncytium-inducing types of human immunodeficiency virus type I by polycations
15. Heparin specifically inhibits binding of V3 loop antibodies to HIV-1 gp120, an effect potentiated by CD4 binding
16. Sulfated carbohydrate compounds prevent microbial adherence by sexually transmitted disease pathogens
17. Identification of envelope V3 loop as the major determinant of CD4 neutralization sensitivity of HIV-1
18. Cell-surface heparan sulfate facilitates human immunodeficiency virus type 1 entry into some cell lines but not primary lymphocytes
19. Inhibitory effect of dextran sulfate and heparin on the replication of human immunodeficiency virus (HIV) in vitro
20. Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus
21. Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B
22. Molecular interaction between HIV-1 major envelope glycoprotein and dextran sulfate
23. Investigations into the mechanism by which sulfated polysaccharides inhibit HIV infection in vitro
24. Human immunodeficiency virus type 1 attachment to HeLa CD4 cells is CD4 independent and gp120 dependent and requires cell surface heparans
25. Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120
26. Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding
27. Role of cell surface glycosaminoglycans of human T cells in human immunodeficiency virus type-1 (HIV-1) infection
28. The physico-chemical factors that govern retrovirus-mediated gene transfer
29. Cell-surface heparan sulfate proteoglycan mediates HIV-1 infection of T-cell lines
30. Anti-HIV-1 activity of chemically modified heparins: Correlation between binding to the V3 loop of gp120 and inhibition of cellular HIV-1 infection in vitro
31. Mediation of human immunodeficiency virus type 1 binding by interaction of cell surface heparan sulfate proteoglycans with the V3 region of envelope gp120-gp41
32. Host cyclophilin A mediates HIV-1 attachment to target cells via heparans
33. Human immunodeficiency virus type 1 hijacks host cyclophilin A for its attachment to target cells
34. Syndecans serve as attachment receptors for human immunodeficiency virus type 1 on macrophages
35. Human immunodeficiency virus type 1 Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions
36. Role of cyclophilin A in the uptake of HIV-1 by macrophages and T lymphocytes
37. Functional association of cyclophilin A with HIV-1 virions
38. The CC-chemokine RANTES increases the attachment of human immunodeficiency virus type 1 to target cells via glycosaminoglycans and also activates a signal transduction pathway that enhances viral infectivity
39. A cell line-based neutralization assay for primary human immunodeficiency virus type 1 isolates that use either the CCR5 or the CXCR4 coreceptor
40. Dextran sulphate, a potent anti-HIV agent in vitro having synergism with zidovudine
41. HIV-1 attachment: Another look
42. Glycosaminoglycan-binding microbial proteins in tissue adhesion and invasion: Key events in microbial pathogenicity