Histidine mutagenesis of Arabidopsis thaliana pyruvate dehydrogenase kinase

European Journal of Biochemistry

Volumn 269, Issue 10, 2002, Pages 2601-2606

  Tovar Mendez, Alejandro ^a   Miernyk, Jan A ^a,b   Randall, Douglas D ^a  

^a University of Missouri   (United States)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

Autophosphorylation; Dehydrogenase complex; Protein kinase; Pyruvate; Regulatory phosphorylation; Site directed mutagenesis

Indexed keywords

PROTEIN HISTIDINE KINASE; PROTEIN SERINE KINASE; PYRUVATE DEHYDROGENASE COMPLEX; PYRUVATE DEHYDROGENASE KINASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARABIDOPSIS; ARTICLE; AUTOPHOSPHORYLATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; ARABIDOPSIS; HISTIDINE; HYDROGEN-ION CONCENTRATION; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN KINASES; RECOMBINANT PROTEINS;

ARABIDOPSIS; ARABIDOPSIS THALIANA; PROKARYOTA;

EID: 0036098840     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2002.02933.x     Document Type: Article

References (30)

1. A trail of research from lipoic acid to α-keto acid dehydrogenase complexes
2. The complex fate of α-ketoacids
3. Site specificity of four pyruvate dehydrogenase kinase isoenzymes toward the three phosphorylation sites of human pyruvate dehydrogenase
4. Regulation of pyruvate dehydrogenase activity through phosphorylation at multiple sites
5. Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms
6. Molecular cloning and expression of the catalytic subunit of bovine pyruvate dehydrogenase phosphatase and sequence similarity with protein phosphatase 2C
7. Crystal structure of the protein serine/threonine phosphatase 2C at 2.0 Å resolution
8. Protein kinases 6. The eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification
9. A new family of protein kinases-the mitochondrial protein kinases
10. Molecular analysis of two pyruvate dehydrogenase kinases from maize
11. Two-component signal transduction
12. An essential role of Glu-243 and His-239 in the phosphotransfer reaction catalyzed by pyruvate dehydrogenase kinase
13. Tetrameric assembly and conservation in the ATP-binding domain of rat branched-chain alpha-ketoacid dehydrogenase kinase
14. Evidence that pyruvate dehydrogenase kinase belongs to the ATPase/kinase superfamily
15. Histidine kinases and response regulator proteins in two-component signaling systems
16. Histidine modifying agents abolish pyruvate dehydrogenase kinase activity
17. Pyruvate dehydrogenase kinase from Arabidopsis thaliana: A protein histidine kinase that phosphorylates serine residues
18. Heterologously expressed inner lipoyl domain of dihydrolipoyl acetyltransferase inhibits ATP-dependent inactivation of pyruvate dehydrogenase complex. Identification of important amino acid residues
19. Expression and characterization of branched-chain alpha-ketoacid dehydrogenase kinase from the rat. Is it a histidine-protein kinase?
20. Nucleotide and deduced amino acid sequences of the pyruvate dehydrogenase kinase from Arabidopsis thaliana (accession, AF039406) (PGR 98-192)
21. PHYLIP-Phylogeny Inference Package Version 3.2
22. Basic local alignment search tool
23. TreeView: An application to display phylogenetic trees on personal computers
24. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
25. GenTHREADER: An efficient and reliable protein fold recognition method for genomic sequences
26. Some kinetic and regulatory properties of the pea mitochondrial pyruvate dehydrogenase complex
27. Partial purification and characterization of the maize mitochondrial pyruvate dehydrogenase complex
28. Molecular cloning, functional expression, and characterization of pyruvate dehydrogenase kinase from anaerobic muscle of the parasitic nematode Ascaris suum
29. Sequence and expression of a gene encoding a pyruvate dehydrogenase kinase homolog of Drosophila melanogaster
30. Structure of pyruvate dehydrogenase kinase. Novel folding pattern for a serine protein kinase