Real-time RT-PCR assay for quantifying cyclin D1 mRNA in B-cell non-Hodgkin’s lymphomas

Modern Pathology

Volumn 15, Issue 5, 2002, Pages 556-564

  Medeiros, L Jeffrey ^a   Hai, Seema ^a   Thomazy, Vilmos A ^a   Estalilla, Oscar C ^a   Romaguera, Jorge ^a   Luthra, Rajyalakshmi ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Cyclin D1; Mantle cell lymphoma; Quantitative reverse transcriptase polymerase chain reaction; Real time

Indexed keywords

CYCLIN D1; EXONUCLEASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA;

ARTICLE; B CELL LYMPHOMA; BLOOD; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; ENZYME ASSAY; FOLLICULAR LYMPHOMA; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; LYMPH NODE; MAJOR CLINICAL STUDY; MANTLE CELL LYMPHOMA; MARGINAL ZONE LYMPHOMA; NONHODGKIN LYMPHOMA; ORGAN DISTRIBUTION; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS;

BONE MARROW; CYCLIN D1; DIGESTIVE SYSTEM; HUMANS; LYMPH NODES; LYMPHOMA, MANTLE-CELL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPLEEN; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0036098588     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3880562     Document Type: Article

References (29)

1. New approach to classifying non-Hodgkin’s lymphomas: Clinical features of the major histologic subtypes
2. PRAD1/cyclin D1 proto-oncogene: Genomic organization, 5′ DNA sequence, and sequence of a tumor-specific rearrangement breakpoint
3. Characterization of a candidate bcl-1 gene
4. Cyclin D1 expression in non-Hodgkin’s lymphomas. Detection by immunohistochemistry
5. Cyclin D1 protein analysis in the diagnosis of mantle cell lymphoma
6. Pathologic diagnosis of mantle cell lymphoma
7. Association of bcl-1 rearrangements with lymphoma of intermediate differentiation
8. Characterization of chromosome 11 translocation breakpoints at the bcl-1 and PRAD1 loci in centrocytic lymphoma
9. Polymerase chain reaction detection of the t(11;14) translocation involving the bcl-1 major translocation cluster in mantle cell lymphoma
10. Detection of the bcl-1 rearrangement at the major translocation cluster in frozen and paraffin-embedded tissues of mantle cell lymphomas by polymerase chain reaction
11. Detection of the chromosomal translocation t(11;14) by polymerase chain reaction in mantle cell lymphomas
12. Real-time 5′ → 3′ exonuclease-based PCR assay for detection of the t(11;14)(q13;q32)
13. Diagnostic utility of fluorescence in situ hybridization in mantle-cell lymphoma
14. Detection of chromosome 11q13 breakpoints by interphase fluorescence in situ hybridzation. A useful ancillary method for the diagnosis of mantle cell lymphoma
15. Detection of 11q13 rearrangements in hematologic neoplasias by double-color fluorescence in situ hybridization
16. Cyclin D1 messenger RNA overexpression as a marker for mantle cell lymphoma
17. PRAD1/cyclin D1 gene overexpression in chronic lymphoproliferative disorders: A highly specific marker of mantle cell lymphoma
18. Differential expression of cyclin D1 in mantle cell lymphoma and other non-Hodgkin’s lymphomas
19. Cell cycle-related variations and tissue-restricted expression of human cyclin D1 protein
20. Detection of specific polymerase chain reaction product by utilizing the 5′ → 3′ exonuclease activity of Thermus aquaticus DNA
21. Real-time quantitative PCR
22. 5′ → 3′ exonuclease-based real-time PCR methods for detecting the t(14;18) and t(11;14) in non-Hodgkin’s lymphomas
23. In situ hybridization and reverse transcription-polymerase chain reaction for cyclin D1 mRNA in the diagnosis of mantle cell lymphoma in paraffin-embedded tissues
24. PRAD1 gene over-expression in mantle-cell lymphoma but not in other low-grade lymphomas, including extranodal lymphoma
25. Quantitative real-time reverse transcription-PCR assay for cyclin D1 expression: Utility in the diagnosis of mantle cell lymphoma
26. Detection of cyclin D1 (bcl-1, PRAD1-) overexpression by a simple competitive reverse transcription-polymerase chain reaction assay in t(11;14)(q13;q32) bearing B-cell malignancies and/or mantle cell lymphoma
27. Transcriptional and post-transcriptional mechanisms induce cyclin-D1 over-expression in B-cell chronic lymphoproliferative disorders
28. Expression of cyclins D-type in B-chronic lymphoproliferative disorders
29. Detection of cyclin D1 overexpression by realtime reverse-transcriptase-mediated quantitative polymerase chain reaction for the diagnosis of mantle cell lymphoma