Pharmacological identification of inward current evoked by dopamine in rat subthalamic neurons in vitro

Neuropharmacology

Volumn 42, Issue 6, 2002, Pages 772-781

  Zhu, Zi Tao ^a   Shen, Ke Zhong ^a   Johnson, Steven W ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Brain slice; D2 receptor; Dopamine; Potassium channel; Subthalamic nucleus

Indexed keywords

2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; BARIUM; DOPAMINE; G PROTEIN COUPLED RECEPTOR; GLUTAMATE RECEPTOR ANTAGONIST; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE DIPHOSPHATE; POTASSIUM CHANNEL; POTASSIUM ION; QUINPIROLE; SULPIRIDE;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; ELECTROPHYSIOLOGY; IN VITRO STUDY; MEMBRANE CONDUCTANCE; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; NERVE CELL; NONHUMAN; PATCH CLAMP; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SUBTHALAMIC NUCLEUS; SYNAPTIC TRANSMISSION;

ACTION POTENTIALS; ANIMALS; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); GUANOSINE DIPHOSPHATE; MALE; MEMBRANE POTENTIALS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE; SUBTHALAMIC NUCLEUS; THIONUCLEOTIDES;

EID: 0036098558     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(02)00035-7     Document Type: Article

References (48)

1. The functional anatomy of basal ganglia disorders
2. The functional anatomy of disorders of the basal ganglia
3. Access resistance and space clamp problems associated with whole-cell patch clamping
4. Localization of dopaminergic markers in the human subthalamic nucleus
5. Alleviation of experimental hemiparkinsonism by high-frequency stimulation of the subthalamic nucleus in primates: A comparison with L-dopa treatment
6. Implication of the subthalamic nucleus in the pathophysiology and pathogenesis of Parkinson's disease
7. Reversal of experimental parkinsonism by lesions of the subthalamic nucleus
8. The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism
9. Subthalamic nucleus neurons switch from single-spike activity to burst-firing mode
10. 2 receptor mRNA
11. Dopaminergic mechanisms in subthalamic nucleus of rat: Analysis using horseradish peroxidase and microiontophoresis
12. Transfected D2 short dopamine receptors inhibit voltage-dependent potassium current in neuroblastoma×glioma hybrid (NG108-15) cells
13. Primate models of movement disorders of basal ganglia origin
14. Behavioral and neurochemical response to haloperidol and SCH-23390 in rats treated neonatally or as adults with 6-hydroxydopamine
15. 2 dopamine receptor activation of potassium channels in identified rat lactotrophs: Whole-cell and single-channel recording
16. The subthalamic nucleus and its connections
17. Appearance of EMG activity and motor asymmetry after unilateral lesions of the dopaminergic innervation to the subthalamic nucleus in the rat
18. Expression of dopamine receptors in the subthalamic nucleus of the rat: Characterization using reverse transcriptase-polymerase chain reaction and autoradiography
19. 1 receptor supersensitivity. I. 6-OHDA lesions of ascending mesemcephalic dopaminergic pathways in the rat
20. Subthalamotomy in parkinsonian monkeys: Behavioural and biochemical analysis
21. Dopamine modulation of two subthreshold currents produces phase shifts in activity of an identified motoneuron
22. Increased subthalamic neuronal activity after nigral dopaminergic lesion independent of disinhibition via the globus pallidus
23. Evidence for a dopaminergic innervation of the subthalamic nucleus in the rat
24. Effects of intrasubthalamic injection of dopamine receptor agonists on subthalamic neurons in normal and 6-hydroxydopamine-lesioned rats: An electrophysiological and c-Fos study
25. Subthalamic nucleus cell firing in the 6-OHDA-treated rat: Basal activity and response to haloperidol
26. A quarter century of brain dopamine research
27. Signal transduction pathways modulated by the D2 subfamily of dopamine receptors
28. Characterization of dopamine receptor binding sites in the subthalamic nucleus
29. Treatment of tremor in Parkinson's disease by subthalamic nucleus stimulation
30. Apomorphine and dopamine D-1 receptor agonists increase the firing rates of subthalamic nucleus neurons
31. The response of subthalamic nucleus neurons to dopamine receptor stimulation in a rodent model of Parkinson's disease
32. Double-blind evaluation of subthalamic nucleus deep brain stimulation in advanced Parkinson's disease
33. 2 receptors to increase potassium conductance in neurones of the rat substantia nigra zona compacta
34. Effect of parkinsonian signs and symptoms of bilateral subthalamic nucleus stimulation
35. 1 receptor binding and mRNA in the brain using receptor autoradiographic and in situ hybridization techniques
36. Dopamine receptor expression in the central nervous system
37. The electrophysiological actions of dopamine and dopaminergic drugs on neurons of the substantia nigra pars compacta and ventral tegemental area
38. Excitatory effect of iontophoretically applied dopamine on identified neurons of the rat subthalamic nucleus
39. Intrasubthalamic injection of 6-hydroxydopamine induces changes in the firing rate and pattern of subthalamic nucleus neurons in the rat
40. Functional anatomy of the basal ganglia. II. The place of subthalamic nucleus and external pallidum in basal ganglia circuitry
41. Presynaptic dopamine D-2 and muscarine M-3 receptors inhibit excitatory and inhibitory transmission to rat subthalamic neurones in vitro
42. D1/D2 dopamine receptor stimulation by L-dopa
43. 2 receptor
44. Systemic administration of NMDA and AMPA receptor antagonists reverses the neurochemical changes induced by nigrostriatal denervation in basal ganglia
45. Evolution of changes in neuronal activity in the subthalamic nucleus of rats with unilateral lesion of the substantia nigra assessed by metabolic and electrophysiological measurements
46. + conductances on spontaneous discharge patterns of developing retinal ganglion cells
47. Dopamine D2 receptor activation depolarizes rat supraoptic neurones in hypothalamic explants