Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5′-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)-related toxicity compared with controls

Clinical Cancer Research

Volumn 8, Issue 5, 2002, Pages 1314-1316

  Innocenti, Federico ^a   Ratain, Mark J ^a   Behnke, Detlev ^b   Raida, Martin ^c   Kliche, Kay Oliver ^c   Pichlmeier, Uwe ^d  

^a UNIVERSITY OF CHICAGO   (United States)

^b Oncoscreen GmbH   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIMETABOLITE; DIHYDROPYRIMIDINE DEHYDROGENASE; FLUOROURACIL; OXIDOREDUCTASE;

ALTERNATIVE RNA SPLICING; CHEMICALLY INDUCED DISORDER; DIARRHEA; ENZYMOLOGY; GENE FREQUENCY; GENETICS; GENOTYPE; HOSPITALIZATION; HUMAN; INTRON; LEUKOPENIA; NEOPLASM; NOTE; PATHOLOGY; POINT MUTATION; STOMATITIS; THROMBOCYTOPENIA; DIAGNOSTIC TEST; DOSE RESPONSE; ENZYME DEFICIENCY; GENE MUTATION; HETEROZYGOSITY; LETTER; PRIORITY JOURNAL;

ALTERNATIVE SPLICING; ANTIMETABOLITES, ANTINEOPLASTIC; DIARRHEA; DIHYDROURACIL DEHYDROGENASE (NADP); FLUOROURACIL; GENE FREQUENCY; GENOTYPE; HUMANS; INTRONS; LEUKOPENIA; NEOPLASMS; OXIDOREDUCTASES; POINT MUTATION; SEVERITY OF ILLNESS INDEX; STOMATITIS; THROMBOCYTOPENIA;

EID: 0036097018     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (0)