Double-blind, randomized, placebo-controlled study of topical 5% acyclovir-1% hydrocortisone cream (ME-609) for treatment of UV radiation-induced herpes labialis

Antimicrobial Agents and Chemotherapy

Volumn 46, Issue 6, 2002, Pages 1870-1874

  Evans, T G ^a   Bernstein, D I ^a   Raborn, G W ^a   Harmenberg, J ^a   Kowalski, J ^a   Spruance, S L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; HYDROCORTISONE; ME 609; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREAM; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG POTENTIATION; HEALING; HERPES LABIALIS; HUMAN; IMMUNOCOMPETENCE; IMMUNOMODULATION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RADIATION INJURY; RANDOMIZED CONTROLLED TRIAL; RECURRENT DISEASE;

ACYCLOVIR; ADMINISTRATION, TOPICAL; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTI-INFLAMMATORY AGENTS; ANTIVIRAL AGENTS; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; FEMALE; HERPES LABIALIS; HUMANS; HYDROCORTISONE; MALE; MIDDLE AGED; OINTMENTS; RECURRENCE; ULTRAVIOLET RAYS;

EID: 0036096362     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.46.6.1870-1874.2002     Document Type: Article

References (11)

1. Combinations of antiviral and anti-inflammatory preparations for the topical treatment of herpes simplex virus assessed using a murine zosteriform infection model
2. Herpes simplex virus zosteriform lesions with adoptive transfer of immune cells: A murine model which mimics human recurrent disease
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4. Treatment of herpes labialis with acyclovir. Review of three clinical trials
5. The natural history of recurrent oral-facial herpes simplex virus infection
6. Th1/Th2-like immunity and resistance to herpes simplex labialis
7. The natural history of ultraviolet radiation-induced herpes simplex labialis and response to therapy with peroral and topical formulations of acyclovir
8. Susceptibility to herpes labialis following multiple experimental exposures to ultraviolet radiation
9. Combination treatment with famciclovir and a topical corticosteroid gel versus famciclovir alone for experimental ultraviolet radiation-induced herpes simplex labialis: A pilot study
10. Penciclovir cream for the treatment of herpes simplex labialis. A randomized, multicenter, double-blind, placebo-controlled trial
11. Peroral famciclovir in the treatment of experimental ultraviolet radiation-induced herpes simplex labialis: A double-blind, dose-ranging, placebo-controlled, multicenter trial