Differential roles for mGluR1 and mGluR5 in the persistent prolongation of epileptiform bursts

Journal of Neurophysiology

Volumn 87, Issue 1, 2002, Pages 621-625

  Merlin, Lisa R ^a  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 3,5 DIHYDROXYPHENYLGLYCINE; 4 CARBOXY 2 METHYLPHENYLGLYCINE; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR ANTAGONIST; PICROTOXIN; RECEPTOR SUBTYPE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EPILEPTIC DISCHARGE; EPILEPTOGENESIS; HIPPOCAMPUS; NONHUMAN; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR SENSITIVITY;

EID: 0036095110     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00579.2001     Document Type: Article

References (22)

1. 2+ signal transduction
2. Altered expression of group I metabotropic glutamate receptors in the hippocampus of amygdala-kindled rats
3. Kindled seizures increase metabotropic glutamate receptor expression and function in the rat supraoptic nucleus
4. Temporal lobe epilepsy associated up-regulation of metabotropic glutamate receptors: Correlated changes in mGluRI mRNA and protein expression in experimental animals and human patients
5. Immunohistochemical distribution of metabotropic glutamate receptor subtypes mGluR1b, mGluR2/3, mGluR4a and mGluR5 in human hippocampus
6. Seizures and neuronal damage induced in the rat by activation of group I metabotropic glutamate receptors with their selective agonist 3,5-dihydroxyphenylglycine
7. (+)-2-Methyl-4-carboxyphenylglycine (LY 367385) selectively antagonises metabotropic mGluR1 receptors
8. Differential expression of metabotropic glutamate receptors in the hippocampus and entorhinal cortex of the rat
9. Long-lasting potentiation of epileptiform bursts by group I mGluRs is NMDA receptor independent
10. 2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist
11. Inhibition of hippocampal kindling by metabotropic glutamate receptor antisense oligonucleotides
12. Cloning, expression, and gene structure of a G protein-coupled glutamate receptor from rat brain
13. 3,5-Dihydroxyphenyl-glycine: A potent agonist of metabotropic glutamate receptors
14. Diversity of calcium signaling by metabotropic glutamate receptors
15. Epileptogenesis up-regulates metabotropic glutamate receptor activation of sodium-calcium exchange current in the amygdala
16. Perisynaptic location of metabotropic glutamate receptors mGluR1 and mGluR5 on dendrites and dendritic spines in the rat hippocampus
17. Sequence and expression of a metabotropic glutamate receptor
18. Group I mGluR-mediated silent induction of long-lasting epileptiform discharges
19. Both mGluR1 and mGluR5 activation contribute to group I mGluR-mediated epileptogenesis
20. Requirement of protein synthesis for group I mGluR-mediated induction of epileptiform discharges
21. Role of group I metabotropic glutamate receptors in the patterning of epileptiform activities in vitro
22. Roles of metabotropic glutamate receptor subtypes in modulation of pentylenetetrazole-induced seizure activity in mice