Role for G protein Gβγ isoform specificity in synaptic signal processing: A computational study

Journal of Neurophysiology

Volumn 87, Issue 5, 2002, Pages 2612-2623

  Bertram, Richard ^a,b   Arnot, Michelle I ^a,b   Zamponi, Gerald W ^a,b  

^a FLORIDA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; COMPLEMENTARY DNA; GUANINE NUCLEOTIDE BINDING PROTEIN; ION CHANNEL;

ARTICLE; CALCIUM TRANSPORT; EMBRYO; HUMAN; HUMAN CELL; KIDNEY CELL; KINETICS; PRIORITY JOURNAL; SIGNAL NOISE RATIO;

EID: 0036092512     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.2002.87.5.2612     Document Type: Article

References (67)

1. Synaptic depression and cortical gain control
2. Range of messenger action of calcium ion and inositol 1,4,5-trisphophate
3. 1A calcium channels by different G protein β subunit isoforms
4. Neurotransmitter inhibition of neuronal calcium currents by changes in channel voltage dependence
5. Differential filtering of two presynaptic depression mechanisms
6. 2+ channel inhibition for neurotransmitter release and facilitation
7. Single-domain/bound calcium hypothesis of transmitter release and facilitation
8. 2+ microdomains on neurotransmitter release
9. Distribution of heterotrimeric G-protein β and γ subunits in the rat brain
10. 2+-dependent regulation in neuronal gene expression
11. Somatostatin inhibits excitatory transmission at rat hippocampal synapses via presynaptic receptors
12. Modulation of N-type calcium channels in bullfrog sympathetic neurons by luteinizing hormone-releasing hormone: Kinetics and voltage dependence
13. 2+ channels in HEK 293 cells
14. Relief of G-protein inhibition of calcium channels and short-term synaptic facilitation in cultured hippocampal neurons
15. Hebbian synapses: Biophysical mechanisms and algorithms
16. Interaction between G proteins and accessory β subunits in the regulation of α1B calcium channels in xenopus oocytes
17. Adenosine modulation of calcium currents and presynaptic inhibition of GABA release in suprachiasmatic and arcuate nucleus neurons
18. B autoreceptor modulation of P/Q-type calcium channels and GABA release in rat suptrachiasmatic nucleus neurons
19. Endogenous regulators of G protein signaling proteins regulate presynaptic inhibition at rat hippocampal synapses
20. Differential occurrence of reluctant openings in G-protein-inhibited N- and P/Q-type calcium channels
21. Contributions of calcium-dependent and calcium-independent mechanisms to presynaptic inhibition at a cerebellar synapse
22. Mechanism and kinetics of heterosynaptic depression at a cerebellar synapse
23. 2+ channels
24. Adenosine increases synaptic facilitation in the in vitro rat hippocampus: Evidence for a presynaptic site of action
25. Calcium channel β subunits differentially regulate the inhibition of N-type channels by individual Gβ isoforms
26. 2+ channels
27. Potential, impedance, and rectifications in membranes
28. Identification of an integration center for the cross-talk between protein kinase C and G protein modulation of N-type calcium channels
29. Emerging roles for RGS proteins in cell signaling
30. 2+ channels by G-protein βγ subunits
31. G-protein-coupled mechanisms and nervous signaling
32. A quantitative description of membrane current and its application to conduction and excitation in nerve
33. Pattern recognition computation using action potential timing for stimulus representation
34. Voltage-dependent modulation of N-type calcium channels by G-protein βγ subunits
35. Local and diffuse synaptic actions of GABA in the hippocampus
36. G protein modulation of N-type calcium channels is facilitated by physical interactions between syntaxin 1A and Gβγ
37. B receptor
38. 2+ channels
39. Reluctant gating of single N-type calcium channels during neurotransmitter-induced inhibition in bullfrog sympathetic neurons
40. Microdomains of high calcium concentration in a presynaptic terminal
41. Sensory neuron N-type calcium currents are inhibited by both voltage-dependent and -independent mechanisms
42. Physiological regulation of G-protein linked signalling
43. Concentration profiles of intracellular calcium in the presence of a diffusible chelator
44. Elementary events underlying voltage-dependent G-protein inhibition of N-type calcium channels
45. 2+ entry
46. Analysis of neural excitability and oscillations
47. Multiple G-protein βγ combinations produce voltage-dependent inhibition of N-type calcium channels in rat superior cervical ganglion neurons
48. Control of neurotransmitter release by presynaptic waveform at the granule cell to Purkinje cell synapse
49. 1 receptors regulate synaptic transmission to rat substantia nigra reticulata neurones
50. Presynaptic muscarinic inhibition in bullfrog sympathetic ganglia
51. Compartmentalization of the submembrane calcium activity during calcium influx and its significance in transmitter release
52. Cleavage of syntaxin prevents G-protein regulation of presynaptic calcium channels
53. P/Q-type calcium channels mediate the activity-dependent feedback of syntaxin-1A
54. 2+ channels by protein kinase C in rat central and peripheral neurons: Disruption of G protein-mediated inhibition
55. 2+ channels and synaptic transmission
56. B receptor
57. Calcium channels, stores, and oscillations
58. Facilitation of N-type calcium current is dependent on the frequency of action potential-like depolarizations in dissociated cholinergic basal forebrain neurons of the guinea pig
59. Adenosine inhibits evoked synaptic transmission primarily by reducing presynaptic calcium influx in area CA1 of hippocampus
60. Presynaptic inhibition of elicited neurotransmitter release
61. 1 subunit
62. Decay of prepulse facilitation of N type calcium channels during G protein inhibition is consistent with binding of a single Gβγ subunit
63. 2+ channels support their inhibition by G proteins
64. Selective regulation of N-type Ca channels by different combinations of G-protein β/γ subunits and RGS proteins
65. Short-term synaptic plasticity
66. Exocytosis: A molecular and physiological perspective