Loops within the CD11c I domain critical for specific recognition of fibrinogen

Biochemical and Biophysical Research Communications

Volumn 292, Issue 3, 2002, Pages 756-760

  Choi, Jeungsook ^a   Nham, Sang Uk ^a  

^a Kangwon National University   (South Korea)

Author keywords

Adhesion; Binding; CD11c; Fibrinogen; I domain; Integrin; Leukocytes

Indexed keywords

AMINO ACID; FIBRINOGEN; GLYCOPROTEIN P 15095; OLIGOPEPTIDE;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIGEN BINDING; ARTICLE; BETA CHAIN; BINDING SITE; CELL ADHESION; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

EID: 0036086751     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2002.6705     Document Type: Article

References (22)

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5. Crystal structure of the A domain from the α subunit of integrin CR3 (CD11b/CD18)
6. Two conformations of the integrin A-domain (I-domain): A pathway for activation?
7. Structural basis of collagen recognition by integrin alpha2beta1
8. 2+-complexed crystal structures
9. Amino acid sequences within the alpha subunit of integrin alpha M beta 2 (Mac-1) critical for specific recognition of C3bi
10. Identification of the binding site for fibrinogen recognition peptide gamma 383-395 within the alpha (M) I-domain of integrin alpha(M)beta2
11. The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands
12. CD11c/CD18 on neutrophils recognizes a domain at the N terminus of the A alpha chain of fibrinogen
13. The leukocyte integrin p150,95 (CD11c/CD18) as a receptor for iC3b. Activation by a heterologous beta subunit and localization of a ligand recognition site to the I domain
14. Characteristics of fibrinogen binding to the domain of CD11c, an α subunit of p150,95
15. cDNA cloning and complete primary structure of the alpha subunit of a leukocyte adhesion glycoprotein, p150,95
16. Distinct ligand binding sites in the I domain of integrin alpha M beta 2 that differentially affect a divalent cation-dependent conformation
17. Mapping the intercellular adhesion molecule-1 and -2 binding site on the inserted domain of leukocyte function-associated antigen-1
18. Fragment E derived from both fibrin and fibrinogen stimulates interleukin-6 production in rat peritoneal macrophages
19. Three-dimensional structural studies on fragments of fibrinogen and fibrin
20. Identification of a novel recognition sequence for integrin alphaM beta2 within the gamma-chain of fibrinogen
21. The structural motif glycine 190-valine 202 of the fibrinogen gamma chain interacts with CD11b/CD18 integrin (alpha M beta 2, Mac-1) and promotes leukocyte adhesion