Effect of mild hypothermia on energy state recovery following transient forebrain ischemia in the gerbil

Experimental Brain Research

Volumn 145, Issue 1, 2002, Pages 83-90

  Kimura, Teruo ^a,b   Sako, Kazuhiro ^a,b   Tanaka, Kunio ^a,b   Kusakabe, Mitsutoshi ^a,b   Tanaka, Tatsuya ^a,b   Nakada, Tsutomu ^b,c  

^a ASAHIKAWA MEDICAL COLLEGE   (Japan)

^b Nayoro City University   (Japan)

^c NIIGATA UNIVERSITY   (Japan)

Author keywords

31P MRS; Energy state recovery; Global ischemia; Mild hypothermia; Transient ischemia

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CORTEX; BRAIN ISCHEMIA; CELL DAMAGE; CELL PH; CONTROLLED STUDY; ENERGY METABOLISM; ENERGY RECOVERY; GERBIL; HIPPOCAMPUS; HYPOTHERMIA; MALE; NEUROPROTECTION; NONHUMAN; PHOSPHATE METABOLISM; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; REPERFUSION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIPYRINE; ASTROCYTES; BODY TEMPERATURE; CEREBRAL CORTEX; CEREBRAL INFARCTION; ENERGY METABOLISM; GERBILLINAE; HIPPOCAMPUS; HYPOTHERMIA, INDUCED; ISCHEMIC ATTACK, TRANSIENT; MALE; NERVE DEGENERATION; NEURONS; PHOSPHOCREATINE; PHOSPHORUS; PROSENCEPHALON; RECOVERY OF FUNCTION; REPERFUSION INJURY;

EID: 0036086723     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-002-1095-8     Document Type: Article

References (43)

1. Controllable graded cerebral ischemia in the gerbil: Studies of cerebral blood flow and energy metabolism by hydrogen clearance and31P NMR spectroscopy
2. Effect of reperfusion following cerebral ischemia on the activity of the mitochondrial respiratory chain in the gerbil brain
3. Deliberate mild intraoperative hypothermia for craniotomy
4. Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury
5. Post-ischemic moderate hypothermia inhibits CA1 hippocampal ischemic neuronal injury
6. Effect of postischaemic hypothermia on the mitochondrial damage induced by ischaemia and reperfusion in the gerbil
7. Neuronal damage, glial response and cerebral metabolism after hypothermic forebrain ischemia in the rat
8. Effect of mild hyperthermia on recovery of metabolic function after global cerebral ischemia in cats
9. The metabolic effects of mild hypothermia on global cerebral ischemia and recirculation in the cat: Comparison to normothermia and hyperthermia
10. Temperature modulation of ischemic neuronal death and inhibition of calcium/calmodulin-dependent protein kinase II in gerbils
11. Moderate hypothermia mitigates neuronal damage in the rat brain when initiated several hours following transient cerebral ischemia
12. Delayed and prolonged post-ischemic hypothermia is neuroprotective in the gerbil
13. The importance of brain temperature in cerebral injury
14. Effects of normothermic versus mild hypothermic forebrain ischemia in rats
15. Interrelationship between increased vascular permeability and acute neuronal damage following temperature-controlled brain ischemia in rats
16. Relationship of brain blood flow and oxygen consumption to perfusion flow rate during profoundly hypothermic cardiopulmonary bypass
17. Detection of free radical activity during transient global ischemia and recirculation: Effect of intraischemic brain temperature modulation
18. Effect of hypothermia upon organic phosphates, glycolytic metabolites, citric acid cycle intermediates and associated amino acids in rat cerebral cortex
19. Mild intraischemic hypothermia suppresses consumption of endogenous antioxidants after temporary focal ischemia in rats
20. Delayed induction of mild hypothermia to reduce infarct volume after temporary middle cerebral artery occlusion in rats
21. Changes of labile metabolites during anoxia in moderately hypo- and hyperthermic rats: Correlation to membrane fluxes of K+
22. Brain temperature during reversible upper respiratory bypass
23. Effect of temperature in focal ischemia of rat brain studied by31P and1H spectroscopic imaging
24. Prevention of postischemic hyperthermia prevents ischemic injury of CA1 neurons in gerbil
25. Effect of moderate hypothermia on lipid peroxidation in canine brain tissue after cardiac arrest and resuscitation
26. The influence of body temperature on infarct volume and thrombolytic therapy in a rat embolic stroke model
27. Failure of prolonged hypocapnia, hypothermia, or hypertension to favorably alter acute stroke in primates
28. The relationship among canine brain temperature, metabolism, and function during hypothermia
29. The influence of mild body and brain hypothermia on ischemic brain damage
30. Temperature dependence of hypoxia-induced calcium accumulation in gerbil hippocampal slices
31. Methodological requirements for accurate measurements of brain and body temperature during global forebrain ischemia of rat
32. Heating of the brain to maintain normothermia during ischemia aggravates brain injury in the rat
33. The significance of brain temperature in focal cerebral ischemia: Histopathological consequences of middle cerebral artery occlusion in the rat
34. Effect of 5-minute ischemia on regional pH and energy state of the gerbil brain: Relation to selective vulnerability of the hippocampus
35. Protection from cerebral ischemia by brain cooling without reduced lactate accumulation in dogs
36. Cerebral blood flow and cerebral oxygen consumption during hypothermia
37. Intracellular pH determination by 31P-NMR technique. The second dissociation constant of phosphoric acid in a biological system
38. Poor recovery of mitochondrial redox state in CA1 after transient forebrain ischemia in gerbils
39. Cerebral ischemia decreases endogenous calcium-dependent protein phosphorylation in gerbil brain
40. Effect of hyperthermia on glutamate release in ischemic penumbra after middle cerebral artery occlusion in rats
41. Reversible focal ischemia in the rat: Effect of halothane, isoflurane and methohexital anesthesia
42. Mild hypothermia prevents ischemic injury in gerbil hippocampus
43. Post-ischemic (1 hour) hypothermia significantly reduces ischemic cell damage in rats subjected to 2 hours of middle cerebral artery occlusion