Gynecological malignancies in elderly patients: Is age 70 a limit to standard-dose chemotherapy? An Italian retrospective toxicity multicentric study

Gynecologic Oncology

Volumn 85, Issue 3, 2002, Pages 445-450

  Ceccaroni, Marcello ^a,b   D'Agostino, Giuseppe ^a   Ferrandina, Gabriella ^a   Gadducci, Angiolo ^c   Di Vagno, Giovanni ^d   Pignata, Sandro ^e   Poerio, Antonella ^a   Salerno, Maria Giovanna ^a   Fanucchi, Antonio ^c   Lapresa, Maria Teresa ^d   Tambaro, Rosa ^e   Scambia, Giovanni ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c UNIVERSITY OF PISA   (Italy)

^d UNIVERSITY OF BARI   (Italy)

^e NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Age; Chemotherapy; Comorbidity; Discontinuation; Dose reduction; Elderly; Oncological; Performance status; Toxicity

Indexed keywords

ANTINEOPLASTIC AGENT; BLEOMYCIN; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; FLUOROURACIL; GEMCITABINE; IFOSFAMIDE; IRINOTECAN; MELPHALAN; NAVELBINE; PACLITAXEL; TOPOTECAN; VINCRISTINE;

AGED; ARTICLE; CANCER CHEMOTHERAPY; CLINICAL TRIAL; COMORBIDITY; DOSE RESPONSE; FEMALE; GYNECOLOGIC CANCER; HEMATOLOGIC DISEASE; HUMAN; MAJOR CLINICAL STUDY; MULTICENTER STUDY; PRIORITY JOURNAL; RETROSPECTIVE STUDY;

EID: 0036083557     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1006/gyno.2002.6631     Document Type: Article

References (27)

1. Geriatric oncology still has a long way to go
2. Trends in cancer mortality in Europe
3. Evaluation of elderly patients for fitness to receive treatment
4. Cancer in the elderly patient. Unique aspects of presentation, management and screening
5. Gynecologic oncologic surgery in the elderly: A retrospective analysis of 213 patients
6. Le vieillissement dèmographique en France. La documentation francaise
7. Epidèmiologie descriptive du cancer du sein de la femme de plus de 70 ans
8. Cancer and the functional status of the elderly
9. Cancer in the aged: An epidemiologic perspective on treatment issues
10. National survey of ovarian carcinoma. IV. Patterns of care and related survival for older patients
11. Pharmacology of antineoplastic agents in the elderly patient
12. Surgical procedures in patients aged 90 years and older
13. Treatment of ovarian cancer in elderly women: Mayo Clinic-North Central Cancer treatment group studies
14. Age does not influence taxol dose intensity in recurrent carcinoma of the ovary
15. Ovarian cancer: Survival and treatment differences by age
16. Is age a barrier to the aggressive treatment of ovarian cancer with paclitaxel and carboplatin?
17. Single agents should be administered in preference to combination chemotherapy for the treatment of patients over 70 years of age with advanced ovarian cancer
18. Epithelial ovarian cancer in the elderly: The Memorian Sloan-Kettering Cancer Center experience
19. Cancer chemotherapy in the elderly
20. Elderly ovarian cancer: Treatment with mitoxantrone-carboplatin
21. Clinical trials and drug toxicity in the elderly: The experience of the Eastern Cooperative Oncology group
22. Age contrasts in patients with advanced epithelial ovarian cancer: The M. D. Anderson Cancer Center experience
23. Pharmacology and organ toxicity of chemotherapy in older patients
24. Age-related declines in hemathopoietic reserve capacity
25. Do elderly cancer patients care about cure? Attitudes to radical gynecologic oncology surgery in the elderly