Protective effect of glycine on renal injury induced by ischemia-reperfusion in vivo

American Journal of Physiology - Renal Physiology

Volumn 282, Issue 3 51-3, 2002, Pages

  Yin, Ming ^a   Zhong, Zhi ^a   Connor, Henry D ^a   Bunzendahl, Hartwig ^a   Finn, William F ^a   Rusyn, Ivan ^a   Li, Xiangli ^a   Raleigh, James A ^a   Mason, Ronald P ^b   Thurman, Ronald G ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Hypoxia; Kidney; Rat

Indexed keywords

FREE RADICAL; GLYCINE; LACTATE DEHYDROGENASE; PIMONIDAZOLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL INFILTRATION; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; FEMALE; FIBROSING ALVEOLITIS; GLOMERULUS FILTRATION RATE; HYPOXIA; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY ISCHEMIA; KIDNEY MEDULLA; KIDNEY TUBULE FUNCTION; LEUKOCYTE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION;

EID: 0036083514     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00011.2001     Document Type: Article

References (40)

1. Acute alcohol produces hypoxia directly in rat liver tissue in vivo: Role of Kupffer cells
2. Evidence that hypoxia markers detect oxygen gradients in liver: Pimonidazole and retrograde perfusion of rat liver
3. Ischemia-induced changes in cell element composition and osmolyte contents of outer medulla
4. Simplification of the anthrone method for the determination of inulin in clearance studies
5. ICAM-1 antisense oligodesoxynucleotides prevent reperfusion injury and enhance immediate graft function in renal transplantation
6. The nature of renal cell injury
7. 14C-misonidazole to hypoxic cells in V 79 spheroids
8. Hydrogen peroxide and superoxide modulate leukocyte adhesion molecule expression and leukocyte endothelial adhesion
9. 2 synthetase inhibitor OKY-046 in a warm ischemia-reperfusion rat model
10. Conservation of structure in ATP-depleted proximal tubules: Role of calcium, polyphosphoinositides, and glycine
11. Mechanism of glycine protection in hypoxic injury: Analogies with glycine receptor
12. Effect of glycine and hypertrophy on renal outer medullary hypoxic injury in ischemia reflow and contrast nephropathy
13. Effect of glycine and hypertrophy on renal outer medullary hypoxic injury in ischemia reflow and contrast nephropathy
14. Cellular and molecular basis of renal repair in acute renal failure
15. Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury
16. In vivo formation of a free radical metabolite of ethanol
17. Body fluids and renal function
18. Neutrophils accentuate ischemia-reperfusion injury in isolated perfused rat kidney
19. Oxygen-derived free radicals in postischemic tissue injury
20. A simple and specific determination of glycine in biological samples
21. Oxygen free radicals in ischemic acute renal failure in the rat
22. Importance of thiols in the reductive binding of 2-nitroimidazoles to macromolecules
23. Component of the AIN-93 diets as improvements in the AIN-76A diet
24. Glycine adjuvant therapy to conventional neuroleptic treatment in schizophrenia: An open-label, pilot study
25. Superoxide and ischemia: Conversion of xanthine dehydrogenase to xanthine oxidase
26. The pathology of chronic renal ischemia
27. The morphology of "acute tubular necrosis" in man: Analysis of 57 renal biopsies and a comparison with the glycerol model
28. Long-term protective effect of UR-12670 after warm renal ischemia in uninephrectomized rats
29. The cell biology of ischemic renal injury
30. Glutathione and glycine in acute renal failure
31. Relationship between cell adenosine triphosphate and glutathione content and protection by glycine against hypoxic proximal tubule cell injury
32. Cytoprotective effects of glycine and glutathione against hypoxic injury to renal tubules
33. Modulation by Gly, Ca, and acidosis of injury-associated unesterified fatty acid accumulation in proximal tubule cells
34. Infusion of glycine does not attenuate in vivo ischemic acute renal failure in the rat
35. PAF antagonist TCV-309 reduces PMN infiltration and enhances early function of 24h preserved rat kidneys with long warm ischemia
36. Ischemia-reperfusion injury of rat kidney relates more to cortical tubular than to microcirculatory disturbances
37. Post-ischemic acute renal failure protects proximal tubules from 02 deprivation injury, possibly by inducing uremia
38. Reductions in renal mass and the nephropathy induced by mercury
39. Cyclosporin A increases hypoxia and free radical production in the rat kidney: Prevention by dietary glycine