Supernatant protein relevant to the activity of membrane-bound enzymes: Studies on lathosterol 5-desaturase

Biochemical and Biophysical Research Communications

Volumn 292, Issue 5, 2002, Pages 1293-1298

  Ishibashi, Teruo ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL FACTOR; CARRIER PROTEIN; CELL PROTEIN; CHOLESTEROL; CYTOCHROME B5; CYTOCHROME B5 REDUCTASE; DETERGENT; FATTY ACID BINDING PROTEIN; LATHOSTEROL; LATHOSTEROL 5 DESATURASE; LIVER ENZYME; MEMBRANE ENZYME; NUCLEOTIDE; OXYGEN; SQUALENE; SQUALENE MONOOXYGENASE; STEROL; STEROL DERIVATIVE; SUPERNATANT PROTEIN FACTOR; TRITIUM; UNCLASSIFIED DRUG;

BIOCHEMISTRY; CATALYSIS; CYTOPLASM; DNA SEQUENCE; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SUBSTRATE COMPLEX; LIPID METABOLISM; MEMBRANE BINDING; MICROSOME; MICROSOME MEMBRANE; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN PROTEIN INTERACTION; REVIEW; SEQUENCE ANALYSIS; SYNTHESIS;

TRITIUM;

EID: 0036082853     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2002.2012     Document Type: Article

References (54)

1. The biological synthesis of cholesterol
2. Specificity and role in cholesterol biosynthesis of a squalene and sterol carrier protein
3. Large scale purification and structural characterization of squalene and sterol carrier protein
4. Intermembrane transfer of 5α-cholest-7-en-3β-ol. Facilitation of supernatant protein (SCP)
5. The mechanism of C-5 (6) double bond introduction in the biosynthesis of cholesterol by rat liver microsomes
6. Partial purification and characterization of lathosterol 5-desaturase from rat liver microsomes
7. Investigation of the component reactions of oxidative sterol demethylation. Study of the aerobic and anaerobic processes
8. 5,7-cholestadien-3β-ol in cholesterol biosynthesis
9. Studies on squalene epoxidase or rat liver
10. Evidence for a noncatalytic carrier protein in cholesterol biosynthesis
11. Squalene epoxidase of rat liver
12. Squalene and sterol carrier protein: Structural properties, lipid-binding, and function in cholesterol biosynthesis
13. Sterol carrier protein hypothesis
14. Effect of a supernatant protein on microsomal squalene epoxidase and 2,3-oxidosqualene-lanosterol cyclase
15. Purification and properties of sterol carrier protein 1
16. Purification of a soluble rat liver protein that stimulates microsomal 4-methyl sterol oxidase activity
17. Purification and properties of a soluble protein activator of rat liver squalene epoxidase
18. Investigation of regulation of microsomal hydroxymethylglutaryl coenzyme A reductase and methyl sterol oxidase of cholesterol biosynthesis
19. Studies on the conversion of enzymatically generated, microsome-bound squalene to sterol
20. Effects of a supernatant protein activator on microsomal squalene-2,3-oxide-lanosterol cyclase
21. Role of supernatant protein factor and anionic phospholipid in squalene uptake and conversion by microsomes
22. Interactions of supernatant protein factor with components of the microsomal squalene epoxidase system: Binding of supernatant protein factor to anionic phospholipids
23. Cytosolic modulators of activities of microsomal enzyme of cholesterol biosynthesis: Role of a cytosolic protein with properties similar to Z-protein (fatty acid-binding protein)
24. A low-molecular-weight protein from rat liver that resembles ligandin in its binding properties
25. Rat liver proteins capable of transferring phosphatidylethanolamine: Purification and transfer activity for other phospholipids and cholesterol
26. Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions
27. The binding of fatty acids to cytoplasmic proteins: Binding to Z protein in liver and other tissues of the rat
28. Z protein: Isolation and characterization of multiple forms in rat liver cytosol
29. Effect of hypolipidemic drugs, nafenopin and clofibrate, on the concentration of ligandin and Z protein in rat liver
30. Fatty acid binding protein. Isolation from rat liver, characterization, and immunochemical quantification
31. Isolation and characterization of fatty acid-binding protein from rat brain
32. Evidence for identifying fatty acids in rat liver glutathione S-transferase and its possible involvement in the secondary structure
33. Fatty-acid-binding proteins: Occurrence of two fatty-acid-binding proteins in bovine liver cytosol and their binding of fatty acids, cholesterol, and other lipophilic ligands
34. Isolation and characterization of the three fractions (DE-I, DE-II and DE-III) of rat-liver Z-protein and the complete primary structure of DE-II
35. Intracellular fatty acid trafficking and the role of cytosolic lipid binding proteins
36. An in vitro reversible interconversion of rat liver fatty acid binding protein having different isoelectric points by virtue of the fatty acid content
37. Reversible conformational changes of rat liver fatty acid binding protein following lipid binding: Circular dichroic and nuclear magnetic resonance analysis
38. s values for cytochrome P-450 and other membrane bound receptors and enzymes
39. Model for the interaction of membrane-bound substrates and enzymes: Hydrolysis of ganglioside GD1a by sialidase of neuronal membranes isolated from calf brain
40. Properties and kinetics of membrane-bound enzymes when both the enzyme and substrate are components of the same microsomal membrane: Studies on lathosterol 5-desaturase
41. Lateral diffusion of lipids and proteins in bilayer membranes
42. Photobleaching measurements of the lateral diffusion of lipids and proteins in artificial phospholipid-bilayer membranes
43. Temperature-induced differential kinetic properties between an initial burst and the following steady state in membrane-bound enzymes: Studies on lathosterol 5-desaturase
44. Fluorescence polarization and viscosities of membrane lipids of 3T3 cells
45. cDNA cloning of the mammalian sterol C5-desaturase and the expression in yeast mutant
46. Cloning, expression, and nutritional regulation of the mammalian Δ-6 desaturase
47. A simple method for displaying the hydropathic character of a protein
48. Cloning, disruption and sequence of the gene encoding yeast C-5 sterol desaturase
49. Deletion of the Candida glabrata ERG3 and ERG11 genes: Effect on cell viability, cell growth, sterol composition, and antifungal susceptibility
50. An arabidopsis mutant deficient in sterol biosynthesis: Heterologous complementation by ERG3 encoding a Δ7-sterol-C-5-desaturase from yeast
51. Membrane-bound enzymes and membrane ultrastructure
52. Regulation of allosteric membrane-bound enzymes through changes in membrane lipid composition
53. The lipid-protein interface in biological membranes
54. Regulation of membrane enzymes by lipids